Gastroenterology News & Articles

Available now at MDLinx Gastroenterology: Ranked summaries of the most clinically-relevant GI literature refreshed every 24 hours, as well as MDLinx Gastroenterology exclusive content

Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in your uniquely diverse field. In addition to general gastroenterology news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.
MDLinx Gastroenterology exclusive content includes: Monthly highlights of the "can't miss" articles chosen by our physician editor, D. Scott Cunningham, MD, PhD; clinical pearls from The Smartest Internist and Smartest Family Physician daily competitions, a collaboration from the editors of MDLinx and Cleveland Clinic Center for Continuing Education; and pearls from our Pediatrics Physician Review quizzes.

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Latest (75) Full Text Articles (1570)

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

261 Steady and dynamic shear rheological properties of gum-based food thickeners used for diet modification of patients with dysphagia: effect of concentration Dysphagia, June 12, 2013 Clinical Article

262 Dermatological side-effects of telaprevir-based triple therapy for chronic hepatitis C in phase III trials in Japan The Journal of Dermatology, June 12, 2013 Clinical Article

263 A meta-analysis of adjuvant therapy after potentially curative treatment for hepatocellular carcinoma Canadian Journal of Gastroenterology, June 12, 2013 Clinical Article

264 Amplification of the met receptor drives resistance to anti-egfr therapies in colorectal cancer Cancer Discovery, June 12, 2013 Clinical Article

265 AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer Journal of Experimental Medicine, June 12, 2013 Clinical Article

266 Colorectal cancer immunotherapy Full Text Discovery Medicine, June 12, 2013 Review Article

267 Predictors for hospitalization and outpatient visits in patients with inflammatory bowel disease: results from the Swiss Inflammatory Bowel Disease Cohort Study European Journal of Gastroenterology & Hepatology, June 12, 2013 Clinical Article

268 Impaired CD4+ T cell restoration in the small vs. large intestine of HIV-1+ South Africans receiving combination antiretroviral therapy The Journal of Infectious Diseases, June 12, 2013 Review Article

269 Antibiotic treatment decreases microbial burden associated with pseudomyxoma peritonei and affects β-catenin distribution Clinical Cancer Research, June 12, 2013 Clinical Article

270 IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction Journal of Experimental Medicine, June 12, 2013 Clinical Article

271 Clinical significance and evolution of hepatic HBsAg expression in HBeAg-positive patients receiving interferon therapy Journal of Gastroenterology, June 12, 2013 Review Article

272 Sugammadex and ideal body weight in bariatric surgery Full Text Anesthesiology Research and Practice, June 12, 2013 Clinical Article

273 Subsquamous intestinal metaplasia after ablation of Barretts esophagus: frequency and importance Current Opinion in Gastroenterology, June 12, 2013 Review Article

274 An increased diversity of HCV isolates were characterized among 393 patients with liver disease in China representing six genotypes, 12 subtypes, and two novel genotype 6 variants Journal of Clinical Virology, June 12, 2013 Review Article

275 Ultrathin endoscope-assisted self-expandable metallic stent placement following initial unsuccessful attempt in malignant upper gastrointestinal obstruction Digestive Endoscopy, June 12, 2013 Clinical Article

276 Perioperative allogenenic blood transfusion is associated with worse clinical outcomes for hepatocellular carcinoma: a meta-analysis PLOS ONE, June 12, 2013 Evidence Based Medicine

277 Endovascular management of nonvariceal upper gastrointestinal hemorrhage European Journal of Gastroenterology & Hepatology, June 12, 2013 Review Article

278 Long noncoding RNA hotair is a prognostic marker for esophageal squamous cell carcinoma progression and survival PLOS ONE, June 12, 2013 Evidence Based Medicine

279 Postcolonoscopy colorectal cancers are preventable: a population-based study Gut, June 12, 2013 Clinical Article

280 Bidirectional associations between overweight and health-related quality of life from 4-11 years: Longitudinal Study of Australian Children International Journal of Obesity, June 12, 2013 Clinical Article

50 available pages First Previous 14 15 16 17 18 19 20 21 22 23 Next Last

Clinical Pearls in Gastroenterology

Eating an early breakfast and dinner when taking PPIs can lower FSSG scores and improve GERD symptoms. (Factors leading to increased FSSG scores: female gender, inadequate sleep, lack of breakfast, antihypertensive agent non-users and dinner just before bedtime.)
33% of patients with suspected GERD are resistant or partially respond to PPIs
Infliximab is the only TNF inhibitor approved by the FDA for ulcerative colitis.

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Highlights in Gastroenterology

What is the best strategy for CRC screening?

As published in the NEJM, researchers in the COLONPREV study (Spain) have reported that fecal immunochemical testing (FIT) is as effective as colonoscopy in the detection of colorectal cancer (CRC). The study population was 50-69 years of age and comprised of 26,703 subjects who underwent a one-time colonoscopy and 26,599 subjects who underwent FIT every 2 years. The primary outcome measure was CRC deaths at 10 years. Participation in screening was greater in the FIT group than the colonoscopy group (34.2% vs. 24.6%). Detection of CRC was similar between the two groups (0.1%). Advanced and non-advanced adenomas were detected more frequently in the colonoscopy group than the FIT group (1.9% vs. 0.9% [OR=2.3] and 4.2% vs. 0.4% [OR=9.8], respectively).

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PPIs increase risk of Clostridium difficile infection

Based on a meta-analysis involving 30 observational studies and 202,965 patients, proton pump inhibitor therapy has been shown to significantly increase the risk of infection with Clostridium difficile (OR = 2.15).

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Metformin improves survival in patients with DM and CRC

In a single institution study involving 424 patients with DM and CRC, those patients treated with metformin had a 30% improvement in OS compared with patients not treated with metformin. Specifically, the metformin-treated patients had a mean survival of 76.9 months compared to 56.9 months.

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Most Popular Gastro Articles

Last month's top read Top Articles of 2012

1 Systematic review: pentoxifylline for the treatment of severe alcoholic hepatitis Alimentary Pharmacology and Therapeutics, April 3, 2013 Review Article

2 Probiotics in the management of irritable bowel syndrome and inflammatory bowel disease Current Opinion in Gastroenterology, February 20, 2013

3 Adalimumab in active ulcerative colitis: A real-life observational study Digestive and Liver Diseases, May 20, 2013

4 Rituximab for the treatment of patients with autoimmune hepatitis who are refractory or intolerant to standard therapy, Canadian Journal of Gastroenterology, May 7, 2013

5 Low allopurinol doses are sufficient to optimize azathioprine therapy in inflammatory bowel disease patients with inadequate thiopurine metabolite concentrations European Journal of Clinical Pharmacology, April 25, 2013

6 Randomised clinical trial comparing sequential and concomitant therapies for Helicobacter pylori eradication in routine clinical practice Gut, May 22, 2013
Exclusive Author Commentary

7 Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study BMC Gastroenterology, May 15, 2013 Free full text

8 Risk of Colorectal Cancer After Colonoscopy Compared With Flexible Sigmoidoscopy or No Lower Endoscopy Among Older Patients in the United States, 1998-2005 Mayo Clinic Proceedings, April 11, 2013

9 Association between Helicobacter pylori infection and the risk of colorectal neoplasia: a systematic review and meta-analysis Colorectal Disease, May 16, 2013 Evidence Based Medicine Review Article

10 The impact of fair colonoscopy preparation on colonoscopy use and adenoma miss rates in patients undergoing outpatient colonoscopy Gastrointestinal Endoscopy, May 6, 2013

11 Management of active crohn disease JAMA, May 23, 2013 Evidence Based Medicine

12 Pilot study: miscellaneous therapy is highly successful for Helicobacter pylori eradication Alimentary Pharmacology and Therapeutics, May 10, 2013

13 Ultrasound-guided vs endoscopic ultrasound-guided fine-needle aspiration for pancreatic cancer diagnosis World Journal of Gastroenterology, April 25, 2013 Free full text

14 Safety and efficacy of peginterferon-α2a plus ribavirin treatment in renal transplant recipients with chronic hepatitis C Journal of Hepatology, May 20, 2013

15 Longitudinal assessment of liver stiffness in patients undergoing antiviral treatment for hepatitis C Digestive and Liver Diseases, May 10, 2013

16 High levels of HBV after the onset lead to chronic infection in patients with acute hepatitis B Clinical Infectious Diseases, May 29, 2013 Review Article

17 Clinical utility of newly developed immunoassays for serum concentrations of adalimumab and anti-adalimumab antibodies in patients with Crohns disease Journal of Gastroenterology, April 15, 2013

18 Statin therapy improves response to interferon alfa and ribavirin in chronic hepatitis C: a systematic review and meta-analysis Antiviral Research , April 23, 2013 Evidence Based Medicine Review Article

19 Cost-effectiveness of Screening for Chronic Hepatitis C Infection in the United States Clinical Infectious Diseases, May 1, 2013

20 The Effect of Rifaximin on Gut Flora and Staphylococcus Resistance Digestive Diseases and Sciences, May 2, 2013

Indexed Journals in Gastroenterology: Gastroenterology, American Journal of Gastroenterology, Gut more

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Gastroenterology News & Articles

Articles

Clinical Pearls in Gastroenterology

Highlights in Gastroenterology

What is the best strategy for CRC screening?

PPIs increase risk of Clostridium difficile infection

Metformin improves survival in patients with DM and CRC

Most Popular Gastro Articles

Other Topics in Gastroenterology