Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Predictive value of early restoration of quality of life in Crohn's disease patients receiving antiTNF agents Journal of Gastroenterology and Hepatology, October 22, 2014    Clinical Article

2 Treatment with immunosuppressive therapy may improve depressive symptoms in patients with inflammatory bowel disease Digestive Diseases and Sciences, October 22, 2014    Clinical Article

3 Hepatitis C virus (HCV) antibody dynamics following acute HCV infection and reinfection among HIV-infected men who have sex with men Clinical Infectious Diseases, October 22, 2014    Clinical Article

4 Higher dietary choline intake is associated with lower risk of nonalcoholic fatty liver in normal-weight Chinese women The Journal of Nutrition, October 22, 2014    Clinical Article

5 The diagnosis of gastro-esophageal reflux disease cannot be made with barium esophagograms Neurogastroenterology & Motility, October 22, 2014    Clinical Article

6 Sofosbuvir-based treatment regimens for chronic, genotype 1 hepatitis C virus infection in U.S. incarcerated populations: A cost-effectiveness analysis Annals of Internal Medicine, October 22, 2014    Clinical Article

7 Pilot clinical trial of hedgehog pathway inhibitor GDC-0449 (vismodegib) in combination with gemcitabine in patients with metastatic pancreatic adenocarcinoma Clinical Cancer Research, October 22, 2014    Clinical Article

8 Biomarkers in hepatic disease: A review focused on critically ill patients Journal of Intensive Care Medicine, October 22, 2014    Review Article    Clinical Article

9 Infrequent development of resistance in genotype 1-6 hepatitis C virus-infected subjects treated with sofosbuvir in phase 2 and 3 clinical trials Clinical Infectious Diseases, October 22, 2014    Clinical Article

10 Phase II study of avatrombopag in thrombocytopenic patients with cirrhosis undergoing an elective procedure Journal of Hepatology, October 22, 2014    Clinical Article

11 Schlafen-11 sensitizes colorectal carcinoma cells to irinotecan Anti-Cancer Drugs, October 22, 2014    Clinical Article

12 Celiac disease as an autoimmune condition Central European Journal of Immunology, October 22, 2014    Review Article

13 Hepatic dimethylarginine-dimethylaminohydrolase1 is reduced in cirrhosis and is a target for therapy in portal hypertension Journal of Hepatology, October 22, 2014    Clinical Article

14 A phase I/II study of XELIRI plus bevacizumab as second-line chemotherapy for Japanese patients with metastatic colorectal cancer (BIX Study) Full Text The Oncologist, October 22, 2014    Clinical Article

15 Correlates of illness severity in infectious mononucleosis Canadian Journal of Infectious Diseases & Medical Microbiology, October 22, 2014    Clinical Article

16 The effect of biofeedback therapy on dyssynergic constipation in patients with or without Irritable Bowel Syndrome Journal of Research in Medical Sciences, October 22, 2014    Clinical Article

17 Comparative validation of assessment criteria for Crohn-like lymphoid reaction in colorectal carcinoma Journal of Clinical Pathology, October 22, 2014    Clinical Article

18 The impact of hepatitis B virus x protein and microRNAs in hepatocellular carcinoma: A comprehensive analysis Tumor Biology, October 22, 2014    Review Article

19 Efficacy of postoperative anticoagulation therapy with enoxaparin for portal vein thrombosis after hepatic resection in patients with liver cancer Thrombosis Research, October 22, 2014    Clinical Article

20 Risk-assessment and pharmacological prophylaxis of venous thromboembolism in hospitalized patients with chronic liver disease Thrombosis Research, October 22, 2014    Clinical Article

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Highlights in Gastroenterology

Risk factors for CHC-related death identified

As reported in the World Journal of Gastroenterology, the following risk factors for chronic hepatitis C (CHC)-related deaths have been identified (n=8250 CHC patients; n=144 CHC-related deaths): α-IFN therapy (AOR=0.53); liver cirrhosis (AOR=2.89); hepatocellular carcinoma versus CHC (AOR=8.82); hypertension (AOR=1.76); alcohol consumption (AOR=1.73); and HBsAg positivity (AOR=22.28).

Decreased PTPN12 expression associated with poor prognosis in HCC

As reported in PLoS ONE, the expression of PTPN12 was decreased in hepatocellular carcinoma tissue samples compared with adjacent normal tissues. Furthermore, decreased PTPN12 expression was associated with tumor recurrence, decreased cancer-specific survival, and decreased recurrence-free survival.

Elevated ?-GT predicts HCC in hepatitis C patients with sustained response

As reported in the Journal of Hepatology, an elevated baseline ɣ-GT level is the strongest predictor of developing HCC in non-cirrhotic patients with hepatitis C and a sustained virologic response (HR = 6.44), followed by age (HR = 3.68).

Other Topics in Gastroenterology

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