Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

1 Postprandial response of bone turnover markers in patients with Crohn’s disease Full Text World Journal of Gastroenterology, July 31, 2014    Clinical Article

2 Extended treatment with pegylated interferon alfa/ribavirin in patients with genotype 2/3 chronic hepatitis C who do not achieve a rapid virological response: final analysis of the randomised N-CORE trial Hepatology International, July 31, 2014    Clinical Article

3 Ethnic disparities in gastric cancer incidence and survival in the USA: an updated analysis of 1992-2009 seer data Digestive Diseases and Sciences, July 31, 2014    Clinical Article

4 Esophageal dilations in eosinophilic esophagitis: A single center experience Full Text World Journal of Gastroenterology, July 31, 2014    Review Article

5 Atrial fibrillation in patients with gastroesophageal reflux disease: A comprehensive review Full Text World Journal of Gastroenterology, July 31, 2014    Review Article

6 Randomised clinical trial: polyethylene glycol 3350 with sports drink vs. polyethylene glycol with electrolyte solution as purgatives for colonoscopy – the incidence of hyponatraemia Alimentary Pharmacology and Therapeutics, July 31, 2014    Clinical Article

7 Viral infection parameters not nucleoside analogue itself correlates with host immunity in nucleoside analogue therapy for chronic hepatitis B Full Text World Journal of Gastroenterology, July 31, 2014    Clinical Article

8 Routine use of thiopurines in maintaining remission in pediatric Crohn’s disease Full Text World Journal of Gastroenterology, July 31, 2014    Clinical Article

9 CKD and nonalcoholic fatty liver disease American Journal of Kidney Diseases, July 31, 2014    Review Article

10 Sorafenib enhances effects of transarterial chemoembolization for hepatocellular carcinoma: a systematic review and meta-analysis Journal of Cancer Research & Clinical Oncology, July 31, 2014    Evidence Based Medicine    Review Article

11 Epidemiology, demographic characteristics and prognostic predictors of ulcerative colitis Full Text World Journal of Gastroenterology, July 31, 2014    Review Article

12 Growth hormone enhances fat-free mass and glutamine availability in patients with short-bowel syndrome: an ancillary double-blind, randomized crossover study American Journal of Clinical Nutrition, July 31, 2014    Clinical Article

13 Hot avulsion: a modification of an existing technique for management of nonlifting areas of a polyp Gastrointestinal Endoscopy, July 31, 2014    Clinical Article

14 Hepatitis C virus reinfection after liver transplantation: Is there a role for direct antiviral agents? Full Text World Journal of Gastroenterology, July 31, 2014    Review Article

15 Factors influencing disease recurrence after ileocolic resection in adult and pediatric onset Crohn's disease The American Journal of Surgery, July 31, 2014    Clinical Article

16 Non-alcoholic fatty liver disease and obesity: Biochemical, metabolic and clinical presentations Full Text World Journal of Gastroenterology, July 31, 2014    Review Article

17 Osteoporosis and fractures in liver disease: Relevance, pathogenesis and therapeutic implications Full Text World Journal of Gastroenterology, July 31, 2014    Review Article

18 The effect of antecolic vs. retrocolic reconstruction on delayed gastric emptying after classic non-pylorus preserving pancreaticoduodenectomy The American Journal of Surgery, July 31, 2014    Clinical Article

19 IL-34 and M-CSF are overexpressed in HCV fibrosis and induce pro-fibrotic macrophages which promote collagen synthesis by hepatic stellate cells Hepatology, July 31, 2014    Clinical Article

20 Associations between IL-1RA polymorphisms and small intestinal bacterial overgrowth among patients with irritable bowel syndrome from India Neurogastroenterology & Motility, July 31, 2014    Clinical Article

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Highlights in Gastroenterology

Infliximab is effective in corticosteroid-refractory ulcerative colitis

As reported in the Journal of Crohn’s & Colitis, treatment of corticosteroid-refractory ulcerative colitis patients with 3 doses of infliximab (n=113) resulted in short- (3 months) and long-term (12 months) colectomy rates of 18.6% and 25.6%, respectively. The RR of colectomy in patients with an elevated CRP and severe endoscopic lesions was 2.15 and 5.13, respectively.

KIT mutations associated with poor prognosis in GISTs

Based on a meta-analysis (18 studies; n=1487) reported in the World Journal of Surgical Oncology, KIT mutations in patients with gastrointestinal stromal tumors (GISTs) are associated with larger tumors (> 5 cm), higher mitotic activity (> 5), more frequent recurrences (OR = 2.06), more frequent metastases (OR = 2.77), and worse 3-year overall survival (OR = 0.47) compared to patients with PDGFRA mutations or wild-type.

SIRT3 expression improves prognosis in gastric cancer

As reported in the World Journal of Surgery, SIRT3 expression improves the prognosis in patients with gastric cancer (n=221). Specifically, the 5-year OS was 51.2% and 39.1% in patients who do and do not express SIRT3, respectively. The 5-year DFS was 49.6% and 38.0% in patients who do and do not express SIRT3, respectively. Patients who do not express SIRT3 are characterized by increased poor cellular differentiation, increased diffuse-type Lauren’s histology, and increases scirrhous-type stromal reactions, suggesting the SIRT3 functions as a tumor suppressor.


Other Topics in Gastroenterology

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