Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Diet in the pathogenesis and treatment of inflammatory bowel diseases Gastroenterology, January 29, 2015    Review Article

2 Successful anti-viral treatment improves survival of patients with advanced liver disease due to chronic hepatitis C Alimentary Pharmacology and Therapeutics, January 29, 2015    Clinical Article

3 Evaluation of proton pump inhibitor-resistant nonerosive reflux disease by esophageal manometry and 24-hour esophageal impedance and ph monitoring Digestion, January 29, 2015    Clinical Article

4 Antimicrobials increase travelers risk of colonization by extended-spectrum betalactamase-producing enterobacteriaceae Clinical Infectious Diseases, January 29, 2015    Clinical Article

5 Gastroesophageal reflux disease is a risk factor for severity of organizing pneumonia Respiration, January 29, 2015    Clinical Article

6 Continuation or reintroduction of bevacizumab beyond progression to first-line therapy in metastatic colorectal cancer: Final results of the randomized BEBYP trial Annals of Oncology, January 29, 2015    Clinical Article

7 FK506-binding protein 5 mRNA levels in ileal mucosa are associated with pouchitis in patients with ulcerative colitis Digestive Diseases and Sciences, January 29, 2015    Clinical Article

8 Variability of oxygenation in possible hepatopulmonary syndrome: effects of requiring two abnormal arterial blood gas results for diagnosis Digestive Diseases and Sciences, January 29, 2015    Clinical Article

9 Aerobic training activates interleukin 10 for colon anticarcinogenic effects. Medicine and Science in Sports and Exercise, January 29, 2015    Clinical Article

10 Prospective pilot study of a single daily dosage of trientine for the treatment of Wilson disease Digestive Diseases and Sciences, January 29, 2015    Clinical Article

11 Clinical course of chronic hepatitis B (CHB) presented with normal ALT in Asian American patients Journal of Viral Hepatitis, January 29, 2015    Clinical Article

12 Protein/peptide arrays to detect anti-Delta genotype 1, 6, 8 specific antibodies among Hepatitis D Virus infected patients by surface plasmon resonance imaging Journal of Clinical Microbiology, January 29, 2015    Clinical Article

13 Helicobacter pylori infection status correlates with serum parameter levels responding to multi-organ functions Digestive Diseases and Sciences, January 29, 2015    Clinical Article

14 Dose-dense biweekly docetaxel combined with 5-fluorouracil as first-line treatment in advanced gastric cancer: A phase II trial Medical Oncology, January 29, 2015    Clinical Article

15 The EPIYA-ABCC motif pattern in CagA of Helicobacter pylori is associated with peptic ulcer and gastric cancer in Mexican population Full Text BMC Gastroenterology, January 29, 2015    Clinical Article

16 Long-term outcomes of endoscopic versus surgical resection of superficial submucosal colorectal cancer Digestive Diseases and Sciences, January 29, 2015    Clinical Article

17 Colorectal cancer screening and prevention in women Digestive Diseases and Sciences, January 29, 2015    Review Article

18 Chronic hepatitis C infection as a risk factor for renal cell carcinoma Digestive Diseases and Sciences, January 29, 2015    Clinical Article

19 Presentation and endoscopic management of sigmoid volvulus in children European Journal of Pediatrics, January 29, 2015    Clinical Article

20 Accuracy of ultrasound and noninvasive markers of fibrosis to identify patients with cirrhosis Digestive Diseases and Sciences, January 29, 2015    Clinical Article

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Highlights in Gastroenterology

Infliximab is effective in corticosteroid-refractory ulcerative colitis

As reported in the Journal of Crohn’s & Colitis, treatment of corticosteroid-refractory ulcerative colitis patients with 3 doses of infliximab (n=113) resulted in short- (3 months) and long-term (12 months) colectomy rates of 18.6% and 25.6%, respectively. The RR of colectomy in patients with an elevated CRP and severe endoscopic lesions was 2.15 and 5.13, respectively.

KIT mutations associated with poor prognosis in GISTs

Based on a meta-analysis (18 studies; n=1487) reported in the World Journal of Surgical Oncology, KIT mutations in patients with gastrointestinal stromal tumors (GISTs) are associated with larger tumors (> 5 cm), higher mitotic activity (> 5), more frequent recurrences (OR = 2.06), more frequent metastases (OR = 2.77), and worse 3-year overall survival (OR = 0.47) compared to patients with PDGFRA mutations or wild-type.

Calcium reduces CRC risk

As reported in the International Journal of Cancer, there is an 8% reduction in CRC risk with each 300 mg/d increase in calcium intake based on 15 studies involving 12305 patients who took 250-1900 mg of calcium/day over a 3.3-16 year follow-up period. The beneficial effect extended beyond 1000 mg/d.

Other Topics in Gastroenterology

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