Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Increased risk of venous thromboembolic events with corticosteroid vs biologic therapy for inflammatory bowel disease Clinical Gastroenterology and Hepatology , July 25, 2014    Clinical Article

2 National estimates of healthcare utilization by individuals with hepatitis C virus infection in the United States Clinical Infectious Diseases, July 25, 2014    Clinical Article

3 Anorectal complications and function in patients suffering from inflammatory bowel disease: a series of patients with long-term follow-up International Journal of Colorectal Disease, July 25, 2014    Clinical Article

4 Plasma vitamin D concentration influences survival outcome after a diagnosis of colorectal cancer Journal of Clinical Oncology, July 25, 2014    Clinical Article

5 Deep-sequencing analysis of the gene encoding the hepatitis C virus nonstructural 3-4a protease confirms a low prevalence of telaprevir-resistant variants at baseline and the end of the REALIZE study The Journal of Infectious Diseases, July 25, 2014    Clinical Article

6 Characteristics of adults in the Hepatitis B Research Network in North America reflect their country of origin and HBV genotype Clinical Gastroenterology and Hepatology , July 25, 2014    Clinical Article

7 Use of selective serotonin reuptake inhibitors and risk of upper gastrointestinal bleeding: a systematic review and meta-analysis Clinical Gastroenterology and Hepatology , July 25, 2014    Evidence Based Medicine    Review Article

8 Alcohol and the risk of Barrett's esophagus: A pooled analysis from the the International BEACON Consortium The American Journal of Gastroenterology, July 25, 2014    Clinical Article

9 Tacrolimus induction followed by maintenance monotherapy is useful in selected patients with moderate-to-severe ulcerative colitis refractory to prior treatment Digestive and Liver Diseases, July 25, 2014    Review Article    Clinical Article

10 Effect of Helicobacter pylori eradication on metachronous gastric cancer after endoscopic resection of gastric tumors: A meta-analysis Helicobacter, July 25, 2014    Evidence Based Medicine

11 Use of endoscopic ultrasound in the preoperative staging of gastric cancer: A multi-institutional study of the U.S. gastric cancer collaborative Journal of the American College of Surgeons, July 25, 2014    Clinical Article

12 Risk of upper gastrointestinal cancers in patients with gastroesophageal reflux disease following a negative screening endoscopy Clinical Gastroenterology and Hepatology , July 25, 2014    Clinical Article

13 The relationship between pancreatic atrophy after steroid therapy and diabetes mellitus in patients with autoimmune pancreatitis Pancreatology, July 25, 2014    Clinical Article

14 Risk and outcomes of chemotherapy-induced diarrhea (CID) among patients with colorectal cancer receiving multi-cycle chemotherapy Cancer Chemotherapy and Pharmacology, July 25, 2014    Clinical Article

15 Applying the Chicago Classification criteria of esophageal motility to a pediatric cohort: effects of patient age and size Neurogastroenterology & Motility, July 25, 2014    Clinical Article

16 Independence does not come with the method - treatment of neurogenic bowel dysfunction in children with myelomeningocele Acta Pediatrica, July 25, 2014    Clinical Article

17 Systematic review: the role of the gut microbiota in chemotherapy- or radiation-induced gastrointestinal mucositis – current evidence and potential clinical applications Alimentary Pharmacology and Therapeutics, July 25, 2014    Review Article

18 Treatment with chemotherapy and dendritic cells pulsed with multiple wilms' tumor 1 (WT1)-specific MHC class I/II-restricted epitopes for pancreatic cancer Clinical Cancer Research, July 25, 2014    Clinical Article

19 Atrial fibrillation in patients undergoing liver transplantation--a single-center experience Transplantation Proceedings, July 25, 2014    Review Article

20 Inactivating mutation in the prostaglandin transporter gene, SLCO2A1, associated with familial digital clubbing, colon neoplasia, and NSAID resistance Cancer Prevention Research, July 25, 2014    Clinical Article

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Highlights in Gastroenterology

SIRT3 expression improves prognosis in gastric cancer

As reported in the World Journal of Surgery, SIRT3 expression improves the prognosis in patients with gastric cancer (n=221). Specifically, the 5-year OS was 51.2% and 39.1% in patients who do and do not express SIRT3, respectively. The 5-year DFS was 49.6% and 38.0% in patients who do and do not express SIRT3, respectively. Patients who do not express SIRT3 are characterized by increased poor cellular differentiation, increased diffuse-type Lauren’s histology, and increases scirrhous-type stromal reactions, suggesting the SIRT3 functions as a tumor suppressor.

Calcium reduces CRC risk

As reported in the International Journal of Cancer, there is an 8% reduction in CRC risk with each 300 mg/d increase in calcium intake based on 15 studies involving 12305 patients who took 250-1900 mg of calcium/day over a 3.3-16 year follow-up period. The beneficial effect extended beyond 1000 mg/d.

Risk factors for intra-abdominal abscesses in Crohn’s disease

As reported in Digestion, uncontrolled CRP at week 14 of therapy with infliximab (OR=1.36) and early loss of response to infliximab (OR=5.36) are independent risk factors for intra-abdominal abscesses in patients with Crohn’s disease.

Other Topics in Gastroenterology

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