Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Pediatric inflammatory bowel disease and depression: treatment implications Current Opinion in Pediatrics, September 15, 2014    Review Article

2 Cirrhosis regression in patients with viral hepatitis B and C: A systematic review Journal of Clinical Gastroenterology, September 15, 2014    Review Article

3 Potential mechanism of corpus-predominant gastritis after PPI therapy in Helicobacter pylori-positive patients with GERD Full Text World Journal of Gastroenterology, September 15, 2014    Clinical Article

4 Depression is not associated with peripheral insulin resistance in patients with chronic hepatitis C infection Journal of Viral Hepatitis, September 15, 2014    Clinical Article

5 The magnitude and duration of Clostridium difficile infection risk associated with antibiotic therapy: A hospital cohort study PLOS ONE, September 15, 2014    Clinical Article

6 The economic impact of the irritable bowel syndrome Alimentary Pharmacology and Therapeutics, September 15, 2014    Review Article

7 Obesity and related risk factors in gastric cardia adenocarcinoma Gastric Cancer, September 15, 2014    Review Article

8 Controlled attenuation parameter for noninvasive assessment of hepatic steatosis using fibroscan: Validation in chronic hepatitis B Digestive Diseases and Sciences, September 15, 2014    Clinical Article

9 Fidaxomicin: A Novel Macrolide Antibiotic for Clostridium difficile Infection The Consultant Pharmacist, September 15, 2014    Review Article

10 Effect of antiplatelet therapy on patients undergoing gastroenterological surgery: thromboembolic risks versus bleeding risks during its perioperative withdrawal World Journal of Surgery, September 15, 2014    Review Article

11 Imaging modalities in pediatric inflammatory bowel disease Current Opinion in Pediatrics, September 15, 2014    Review Article

12 Hepatic artery pseudoaneurysms: A single-center experience Annals of Vascular Surgery, September 15, 2014    Clinical Article

13 Higher efficacy of antiviral therapy after major hepatectomy in patients with hepatitis B virus-related hepatocellular carcinoma of less than 3 cm European Journal of Gastroenterology & Hepatology, September 15, 2014    Clinical Article

14 Bone mineral density and expression of vitamin D receptor-dependent calcium uptake mechanisms in the proximal small intestine after bariatric surgery British Journal of Surgery, September 15, 2014    Clinical Article

15 Phosphorylation of hepatitis C virus RNA polymerases Ser29 and Ser42 by protein kinase C-related kinase 2 regulates viral RNA replication Journal of Virology, September 15, 2014    Clinical Article

16 Caesarean section to prevent transmission of hepatitis B: A meta-analysis Canadian Journal of Gastroenterology, September 15, 2014    Evidence Based Medicine

17 Higher free serum cortisol is associated with worse survival in acute variceal bleeding because of cirrhosis: a prospective study European Journal of Gastroenterology & Hepatology, September 15, 2014    Clinical Article

18 Practical approach in hepatitis B e antigen-negative individuals to identify treatment candidates Full Text World Journal of Gastroenterology, September 15, 2014    Clinical Article

19 Arginine supplementation in prevention of necrotizing enterocolitis in the premature infant: an updated systematic review Full Text BMC Pediatrics, September 15, 2014    Evidence Based Medicine    Review Article

20 Multicenter study on the discontinuation and efficacy of chronic hepatitis C treatment in the Spanish penitentiary population (EPIBAND study) European Journal of Gastroenterology & Hepatology, September 15, 2014    Clinical Article

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Highlights in Gastroenterology

KIT mutations associated with poor prognosis in GISTs

Based on a meta-analysis (18 studies; n=1487) reported in the World Journal of Surgical Oncology, KIT mutations in patients with gastrointestinal stromal tumors (GISTs) are associated with larger tumors (> 5 cm), higher mitotic activity (> 5), more frequent recurrences (OR = 2.06), more frequent metastases (OR = 2.77), and worse 3-year overall survival (OR = 0.47) compared to patients with PDGFRA mutations or wild-type.

Risk factors for CHC-related death identified

As reported in the World Journal of Gastroenterology, the following risk factors for chronic hepatitis C (CHC)-related deaths have been identified (n=8250 CHC patients; n=144 CHC-related deaths): α-IFN therapy (AOR=0.53); liver cirrhosis (AOR=2.89); hepatocellular carcinoma versus CHC (AOR=8.82); hypertension (AOR=1.76); alcohol consumption (AOR=1.73); and HBsAg positivity (AOR=22.28).

Elevated ?-GT predicts HCC in hepatitis C patients with sustained response

As reported in the Journal of Hepatology, an elevated baseline ɣ-GT level is the strongest predictor of developing HCC in non-cirrhotic patients with hepatitis C and a sustained virologic response (HR = 6.44), followed by age (HR = 3.68).

Other Topics in Gastroenterology

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