Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature
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1 Bolus administration of steroid therapy is more favorable than the conventional use in preventing decrease of bone density and the increase of body fat percentage in patients with inflammatory bowel disease Journal of Crohn's and Colitis, August 22, 2014    Clinical Article

2 Vitamin D level and sustained virologic response to interferon-based antiviral therapy in chronic hepatitis C: a systematic review and meta-analysis Journal of Hepatology, August 22, 2014    Evidence Based Medicine    Review Article

3 Long-term use of antibiotics and proton-pump inhibitors predict development of infections in patients with cirrhosis Clinical Gastroenterology and Hepatology , August 22, 2014    Clinical Article

4 Zinc supplementation in young children: A review of the literature focusing on diarrhoea prevention and treatment Clinical Nutrition, August 22, 2014    Review Article

5 Gut microbiota in preterm infants with gross blood in stools: A prospective, controlled study Early Human Development, August 22, 2014    Clinical Article

6 Telotristat etiprate, a novel serotonin synthesis inhibitor, in patients with carcinoid syndrome and diarrhea not adequately controlled by octreotide Endocrine-Related Cancer, August 22, 2014    Clinical Article

7 Influence of repeated infusion of capsaicin-contained red pepper sauce on esophageal secondary peristalsis in humans Neurogastroenterology & Motility, August 22, 2014    Clinical Article

8 Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up Hepatology, August 22, 2014    Clinical Article

9 Factors associated with hepatitis B vaccine series completion in a randomized trial for injection drug users reached through syringe exchange programs in three US cities Full Text BMC Public Health, August 22, 2014    Clinical Article

10 Minimal benefit of earlier-than-recommended repeat colonoscopy among US Medicare enrollees following a negative colonoscopy Alimentary Pharmacology and Therapeutics, August 22, 2014    Clinical Article

11 Magnetic resonance enterography in pregnant women with Crohn's disease: case series and literature review Full Text BMC Gastroenterology, August 22, 2014    Review Article

12 Effect of gastrointestinal resection on sunitinib exposure in patients with GIST Full Text BMC Cancer, August 22, 2014    Clinical Article

13 The risk of malignancy associated with the use of biological agents in patients with inflammatory bowel disease Gastroenterology Clinics of North America, August 22, 2014    Review Article

14 Combination of hepatocyte specific delivery and transformation dependent expression of shRNA inducing transcriptional gene silencing of c-Myc promoter in hepatocellular carcinoma cells Full Text BMC Cancer, August 22, 2014    Clinical Article

15 Colorectal cancer risk information presented by a nonphysician assistant does not increase screening rates Full Text Canadian Family Physician, August 22, 2014    Clinical Article

16 Risk stratification of patients with Barrett's esophagus and low-grade dysplasia or indefinite for dysplasia Clinical Gastroenterology and Hepatology , August 22, 2014    Clinical Article

17 Alpha-fetoprotein level as a biomarker of liver fibrosis status: a cross-sectional study of 619 consecutive patients with chronic hepatitis B Full Text BMC Gastroenterology, August 22, 2014    Clinical Article

18 A heterogeneous hierarchy of co-regulatory receptors regulates exhaustion of HCV-specific CD8 T cells in patients with chronic hepatitis C Journal of Hepatology, August 22, 2014    Clinical Article

19 Short sleep duration reduces the risk of nonalcoholic fatty liver disease onset in men: a community-based longitudinal cohort study Journal of Gastroenterology, August 22, 2014    Review Article

20 Systematic review of clinical features of suspected colorectal cancer in primary care Full Text Canadian Family Physician, August 22, 2014    Evidence Based Medicine    Review Article

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Highlights in Gastroenterology

Increased MMP-9 expression associated with poor prognosis in CRC

As reported in the World Journal of Surgical Oncology, the expression of MMP-9 in colon cancer tissues was increased compared to distal normal mucosa (69.1% vs. 2.9%). Increased MMP-9 expression was associated with lymph node metastasis, Duke stage, and decreased survival.

Elevated ?-GT predicts HCC in hepatitis C patients with sustained response

As reported in the Journal of Hepatology, an elevated baseline ɣ-GT level is the strongest predictor of developing HCC in non-cirrhotic patients with hepatitis C and a sustained virologic response (HR = 6.44), followed by age (HR = 3.68).

KIT mutations associated with poor prognosis in GISTs

Based on a meta-analysis (18 studies; n=1487) reported in the World Journal of Surgical Oncology, KIT mutations in patients with gastrointestinal stromal tumors (GISTs) are associated with larger tumors (> 5 cm), higher mitotic activity (> 5), more frequent recurrences (OR = 2.06), more frequent metastases (OR = 2.77), and worse 3-year overall survival (OR = 0.47) compared to patients with PDGFRA mutations or wild-type.


Other Topics in Gastroenterology

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