Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature
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1 Induction of clinical and colonoscopic remission of mild–to–moderate ulcerative colitis with budesonide MMX 9 mg: pooled analysis of two phase 3 studies Alimentary Pharmacology and Therapeutics, January 26, 2015    Clinical Article

2 Randomized trial of interferon- and ribavirin-free ombitasvir/paritaprevir/ritonavir in treatment-experienced HCV-infected patients Hepatology, January 26, 2015    Clinical Article

3 Pharmacokinetics of sublingual buprenorphine and naloxone in subjects with mild to severe hepatic impairment (Child-Pugh classes A, B, and C), in hepatitis C virus-seropositive subjects, and in healthy volunteers Clinical Pharmacokinetics, January 26, 2015    Clinical Article

4 Bevacizumab continuation versus no continuation after first-line chemotherapy plus bevacizumab in patients with metastatic colorectal cancer: A randomized phase III non-inferiority trial Annals of Oncology, January 26, 2015    Clinical Article

5 Irritable bowel syndrome is significantly associated with somatisation in 840 patients, which may drive bloating Alimentary Pharmacology and Therapeutics, January 26, 2015    Clinical Article

6 All-oral 12-week treatment with daclatasvir plus sofosbuvir in patients with hepatitis C virus genotype 3 infection: ALLY-3 Phase 3 Study Hepatology, January 26, 2015    Clinical Article

7 The benefit of microsatellite instability is attenuated by chemotherapy in stage II and stage III gastric cancer: Results from a large cohort with subgroup analyses International Journal of Cancer, January 26, 2015    Clinical Article

8 Epirubicin, oxaliplatin, and capectabine is just as "MAGIC"al as epirubicin, cisplatin, and fluorouracil perioperative chemotherapy for resectable locally advanced gastro-oesophageal cancer Journal of Cancer Research and Therapeutics, January 26, 2015    Clinical Article

9 A novel assay for easy and rapid quantification of Helicobacter pylori adhesion Helicobacter, January 26, 2015    Clinical Article

10 Efficacy and cost-effectiveness of screening colonoscopy according to the adenoma detection rate United European Gastroenterology Journal, January 26, 2015    Clinical Article

11 A concise review of non-alcoholic fatty liver disease Atherosclerosis, January 26, 2015    Review Article

12 Pancreaticogastrostomy versus pancreaticojejunostomy after pancreaticoduodenectomy: A meta-analysis of randomized controlled trials The American Journal of Surgery, January 26, 2015    Evidence Based Medicine    Clinical Article

13 A comparative study of set up variations and bowel volumes in supine versus prone positions of patients treated with external beam radiation for carcinoma rectum Journal of Cancer Research and Therapeutics, January 26, 2015    Clinical Article

14 Nonsteroidal anti-inflammatory drugs and the risk for anastomotic failure a report from Washington State’s Surgical Care and Outcomes Assessment Program (SCOAP) JAMA Surgery, January 26, 2015    Clinical Article

15 Characteristics of nighttime reflux assessed using multichannel intraluminal impedance pH monitoring and a portable electroencephalograph Diseases of the Esophagus, January 26, 2015    Clinical Article

16 Dosimetric comparison between Volumetric Modulated Arc Therapy (VMAT) vs Intensity Modulated Radiation Therapy (IMRT) for radiotherapy of mid esophageal carcinoma Journal of Cancer Research and Therapeutics, January 26, 2015    Clinical Article

17 Reliability of risk-based screening for hepatitis C virus infection among pregnant women in Egypt Journal of Infection, January 26, 2015    Clinical Article

18 Treatment of anastomotic leaks with metallic stent after esophagectomies Diseases of the Esophagus, January 26, 2015    Clinical Article

19 Hepatocyte buds derived from progenitor cells repopulate regions of parenchymal extinction in human cirrhosis Hepatology, January 26, 2015    Clinical Article

20 Computer-aided assessment of hepatic contour abnormalities as an imaging biomarker for the prediction of hepatocellular carcinoma development in patients with chronic hepatitis C European Journal of Radiology, January 26, 2015    Clinical Article

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Highlights in Gastroenterology

Elevated ?-GT predicts HCC in hepatitis C patients with sustained response

As reported in the Journal of Hepatology, an elevated baseline ɣ-GT level is the strongest predictor of developing HCC in non-cirrhotic patients with hepatitis C and a sustained virologic response (HR = 6.44), followed by age (HR = 3.68).

Calcium reduces CRC risk

As reported in the International Journal of Cancer, there is an 8% reduction in CRC risk with each 300 mg/d increase in calcium intake based on 15 studies involving 12305 patients who took 250-1900 mg of calcium/day over a 3.3-16 year follow-up period. The beneficial effect extended beyond 1000 mg/d.

Risk factors for CHC-related death identified

As reported in the World Journal of Gastroenterology, the following risk factors for chronic hepatitis C (CHC)-related deaths have been identified (n=8250 CHC patients; n=144 CHC-related deaths): α-IFN therapy (AOR=0.53); liver cirrhosis (AOR=2.89); hepatocellular carcinoma versus CHC (AOR=8.82); hypertension (AOR=1.76); alcohol consumption (AOR=1.73); and HBsAg positivity (AOR=22.28).


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