We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Diffusion-weighted magnetic resonance imaging is effective to detect ileocolonic ulcerations in Crohn's diseaseAlimentary Pharmacology and Therapeutics, June 30, 2015  Clinical Article
2Efficacy and safety of sofosbuvir-based triple therapy in hepatitis C genotype 4 infectionDigestive and Liver Diseases, June 30, 2015  Clinical Article
3Proton pump inhibitors are associated with lower gastrointestinal tract bleeding in low-dose aspirin users with ischaemic heart diseaseDigestive and Liver Diseases, June 30, 2015  Clinical Article
4Use of Chamomilla recutita in the prevention and treatment of oral mucositis in patients undergoing hematopoietic stem cell transplantation: A randomized, controlled, phase II clinical trialCancer Nursing, June 30, 2015  Clinical Article
5Analyses of the post-reflux swallow-induced peristaltic wave index and nocturnal baseline impedance parameters increase the diagnostic yield of patients with reflux diseaseClinical Gastroenterology and Hepatology , June 30, 2015  Review Article
65-Fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) plus sunitinib or bevacizumab as first-line treatment for metastatic colorectal cancer: A randomized Phase IIb studyCancer Management and Research, June 30, 2015  Full Text  Clinical Article
7Recombinant streptokinase vs hydrocortisone suppositories in acute hemorrhoids: A randomized controlled trialWorld Journal of Gastroenterology, June 30, 2015  Full Text  Clinical Article
8Prenatal risk factors and outcomes in gastroschisis: a meta-analysisPediatrics, June 30, 2015  Evidence Based Medicine  Review Article
9Treatment of metastatic colorectal cancer: focus on panitumumabCancer Management and Research, June 30, 2015  Full Text  Review Article
10Optimizing the management of patients with BCLC stage-B hepatocellular carcinoma: Modern surgical resection as a feasible alternative to transarterial chemoemolizationEuropean Journal of Surgical Oncology, June 30, 2015  Clinical Article

Show Me:

We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Risk of bowel cancer reduced by taking aspirin for Lynch syndrome patientsUniversity of Melbourne News, June 29, 2015
2Tiny particles in blood useful for early diagnosis of pancreatic cancerThe University of Texas MD Anderson Cancer Center, June 26, 2015
3UAB among the first to enroll in national clinical trial for novel fecal incontinence treatmentUAB Medicine, June 26, 2015
4Maternal stress alters offspring gut and brain through vaginal microbiomeEndocrine Society News, June 26, 2015
5Study identifies multiple genetic changes linked to increased pancreatic cancer riskJohns Hopkins Medicine, June 26, 2015
6A gel that can make drugs last longerAgency for Science, Technology and Research (A*STAR) News, June 26, 2015
7Discovery targets dormant bowel cancer cells before they form secondary tumoursUniversity of Melbourne News, June 26, 2015
8New approach holds promise for earlier, easier detection of colorectal cancerCalifornia Institute of Technology News, June 26, 2015
9Researchers develop new breath test to diagnose oesophageal and gastric cancerImperial College London Health News, June 25, 2015
10Saliva exoneratedHarvard Medical School News, June 25, 2015

Show Me:

Increased MMP-9 expression associated with poor prognosis in CRC

As reported in the World Journal of Surgical Oncology, the expression of MMP-9 in colon cancer tissues was increased compared to distal normal mucosa (69.1% vs. 2.9%). Increased MMP-9 expression was associated with lymph node metastasis, Duke stage, and decreased survival.

SIRT3 expression improves prognosis in gastric cancer

As reported in the World Journal of Surgery, SIRT3 expression improves the prognosis in patients with gastric cancer (n=221). Specifically, the 5-year OS was 51.2% and 39.1% in patients who do and do not express SIRT3, respectively. The 5-year DFS was 49.6% and 38.0% in patients who do and do not express SIRT3, respectively. Patients who do not express SIRT3 are characterized by increased poor cellular differentiation, increased diffuse-type Lauren’s histology, and increases scirrhous-type stromal reactions, suggesting the SIRT3 functions as a tumor suppressor.

Decreased PTPN12 expression associated with poor prognosis in HCC

As reported in PLoS ONE, the expression of PTPN12 was decreased in hepatocellular carcinoma tissue samples compared with adjacent normal tissues. Furthermore, decreased PTPN12 expression was associated with tumor recurrence, decreased cancer-specific survival, and decreased recurrence-free survival.

Are YOU the Smartest Doc in America?

The Smartest Doc from MDLinx keeps you current with a competitive edge, pitting colleagues against one other for the title of The Smartest Doc in America.

Take the Challenge

Clinical Pearls

Clinical Pearl from Smartest DocCeliac disease is at least twice as common in cirrhotic patients as in the general population.

Clinical Pearl from Smartest DocIBD patients are at increased risk for gastrointestinal and extraintestinal malignancy.

Clinical Pearl from Smartest DocTelomere shortening and advanced-stage biliary disease strongly support the telomere hypothesis of human cirrhosis.

New! Conference Interviews

Video Interview

Conference reports and videos; experts discuss new research! See the Latest Highlights