We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Effectiveness of probiotic therapy for the prevention of relapse in patients with inactive ulcerative colitisWorld Journal of Gastroenterology, May 29, 2015  Full Text  Clinical Article
2Proton pump inhibitors therapy vs H2 receptor antagonists therapy for upper gastrointestinal bleeding after endoscopy: A meta-analysisWorld Journal of Gastroenterology, May 29, 2015  Full Text  Clinical Article  Evidence Based Medicine
3The efficacy and safety of daclatasvir in the treatment of chronic hepatitis C virus infectionAlimentary Pharmacology and Therapeutics, May 29, 2015  Review Article
4Safety, tolerability, and efficacy of oxaliplatin-based adjuvant chemotherapy after curative resection of hepatic or extrahepatic metastases of Stage IV colorectal cancerCancer Chemotherapy and Pharmacology, May 29, 2015  Clinical Article
5Phase II study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced pancreatic cancerCancer Chemotherapy and Pharmacology, May 29, 2015  Clinical Article
6Changing 14-year trends in the epidemiology of hepatitis B virus infection in rural and urban Central–Eastern European areasJournal of Viral Hepatitis, May 29, 2015  Clinical Article
7Prevention of liver cancer through the early detection of risk-related behavior among hepatitis B or C carriersCancer Nursing, May 29, 2015  Clinical Article
8Comparison of liver transplant-related survival benefit in patients with vs without hepatocellular carcinoma in the United StatesGastroenterology, May 29, 2015  Clinical Article
9Association of type 2 diabetes mellitus and the risk of colorectal cancer: A meta-analysis and systematic reviewWorld Journal of Gastroenterology, May 29, 2015  Full Text  Evidence Based Medicine  Review Article
10Beyond endoscopic mucosal healing in UC: histological remission better predicts corticosteroid use and hospitalisation over 6 years of follow-upGut, May 29, 2015  Clinical Article

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We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1FDA approves two therapies to treat IBS-DFDA Press Announcements, May 29, 2015
2Researchers developing new targeted and immune therapies for colorectal cancer molecular subtypesFox Chase Cancer Center News, May 29, 2015
3Diagnosing cancer with help from bacteriaMassachusetts Institute of Technology Research News, May 29, 2015
4Complex signaling between blood and stem cells controls regeneration in fly gutBuck Institute for Research on Aging News, May 28, 2015
5University Hospital of Bellvitge uses a new app for patients with inflammatory bowel diseaseIDIBELL-Bellvitge Biomedical Research Institute News, May 28, 2015
6Research News Tpl2 enzyme may be target for treating autoimmune diseasesUniversity of Georgia Research News, May 27, 2015
7New demonstration project links colorectal cancer screening to discussion and testing for hepatitis CAmerican College of Gastroenterology News, May 27, 2015
8Researchers discover tumor molecule that causes spread of pancreatic cancerFred Hutchinson Cancer Research Center News, May 26, 2015
9In study, skipping meals is linked to abdominal weight gainOhio State University News, May 21, 2015
10Helping doctors predict what's next for patients diagnosed with Hepatitis CUniversity of Michigan Health System, May 21, 2015

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Increased MMP-9 expression associated with poor prognosis in CRC

As reported in the World Journal of Surgical Oncology, the expression of MMP-9 in colon cancer tissues was increased compared to distal normal mucosa (69.1% vs. 2.9%). Increased MMP-9 expression was associated with lymph node metastasis, Duke stage, and decreased survival.

Decreased PTPN12 expression associated with poor prognosis in HCC

As reported in PLoS ONE, the expression of PTPN12 was decreased in hepatocellular carcinoma tissue samples compared with adjacent normal tissues. Furthermore, decreased PTPN12 expression was associated with tumor recurrence, decreased cancer-specific survival, and decreased recurrence-free survival.

Risk factors for intra-abdominal abscesses in Crohn’s disease

As reported in Digestion, uncontrolled CRP at week 14 of therapy with infliximab (OR=1.36) and early loss of response to infliximab (OR=5.36) are independent risk factors for intra-abdominal abscesses in patients with Crohn’s disease.

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Clinical Pearls

Clinical Pearl from Smartest DocAdding probiotics to conventional therapy may induce and maintain remission in patients with ulcerative colitis.

Clinical Pearl from Smartest DocFatty pancreas is difficult to assess.

Clinical Pearl from Smartest DocVigilance and screening for non-melanoma skin cancer is recommended in patients being treated for IBD.

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