We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Impact of immunosuppressive therapy on hepatitis B vaccination in inflammatory bowel diseasesEuropean Journal of Gastroenterology & Hepatology, July 07, 2015  Clinical Article
2Clinical management of patients with parenteral nutrition–dependent short bowel syndrome during teduglutide therapyJournal of Parenteral and Enteral Nutrition, July 07, 2015  Clinical Article
3A phase II study of biweekly S-1 and paclitaxel (SPA) as first-line chemotherapy in patients with metastatic or advanced gastric cancerCancer Chemotherapy and Pharmacology, July 07, 2015  Clinical Article
4Prevalence of coeliac disease in idiopathic hypoparathyroidism and effect of gluten free diet on calcaemic controlClinical Endocrinology, July 07, 2015  Clinical Article
5Liver fibrosis by transient elastography and virologic outcomes after introduction of tenofovir in lamivudine-experienced adults with HIV and hepatitis B virus coinfection in GhanaClinical Infectious Diseases, July 07, 2015  Clinical Article
6Efficacy and safety of diosmectite in acute childhood diarrhoea: A meta-analysisArchives of Diseases in Childhood, July 07, 2015  Evidence Based Medicine
7Safety of gadoxetate disodium: results from six clinical phase IV studies in 8194 patientsActa Radiologica, July 07, 2015  Clinical Article
8Serum hyaluronic acid in chronic viral hepatitis B and C: A biomarker for assessing liver fibrosis in chronic hemodialysis patientsInternational Urology and Nephrology, July 07, 2015  Clinical Article
9Risk factors for 30-day readmission following colorectal surgery: A systematic reviewJournal of Surgical Research, July 07, 2015  Evidence Based Medicine  Review Article
10Somatostatin analogues improve health-related quality of life in polycystic liver disease: a pooled analysis of two randomised, placebo-controlled trialsAlimentary Pharmacology and Therapeutics, July 07, 2015  Clinical Article

Show Me:

We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Colon cancer: Taking a step back to move forwardWeizmann Institute of Science News, July 07, 2015
2The importance of placebos to medical careBeth Israel Deaconess Medical Center, July 06, 2015
3Cause of acute liver failure in young children discoveredTechnische Universität München, July 06, 2015
4Singapore team's discovery of new genomic aberrations of gastric cancer could pave the way for precision medicineAgency for Science, Technology and Research (A*STAR) News, July 06, 2015
5Abdominal blood clots may indicate undiagnosed cancerAarhus University Health News, July 06, 2015
6World GI 2015: Studies confirm regorafenib benefit in pre-treated metastatic colorectal cancerEuropean Society for Medical Oncology News, July 06, 2015
7McMaster researchers test fecal transplantation to treat ulcerative colitisMcMaster University Faculty of Health Sciences News, July 06, 2015
8Discovery promises new treatments to thwart colon cancerSt. Jude Children's Research Hospital News, July 06, 2015
9World GI 2015: Second-line cetuximab active beyond progression in quadruple wild-type patients with metastatic colorectal cancerEuropean Society for Medical Oncology News, July 06, 2015
10Anxiety increases the risk of gastrointestinal infection and long-term complicationsFlanders Institute for Biotechnology (VIB) News, July 03, 2015

Show Me:

Calcium reduces CRC risk

As reported in the International Journal of Cancer, there is an 8% reduction in CRC risk with each 300 mg/d increase in calcium intake based on 15 studies involving 12305 patients who took 250-1900 mg of calcium/day over a 3.3-16 year follow-up period. The beneficial effect extended beyond 1000 mg/d.

Increased MMP-9 expression associated with poor prognosis in CRC

As reported in the World Journal of Surgical Oncology, the expression of MMP-9 in colon cancer tissues was increased compared to distal normal mucosa (69.1% vs. 2.9%). Increased MMP-9 expression was associated with lymph node metastasis, Duke stage, and decreased survival.

SIRT3 expression improves prognosis in gastric cancer

As reported in the World Journal of Surgery, SIRT3 expression improves the prognosis in patients with gastric cancer (n=221). Specifically, the 5-year OS was 51.2% and 39.1% in patients who do and do not express SIRT3, respectively. The 5-year DFS was 49.6% and 38.0% in patients who do and do not express SIRT3, respectively. Patients who do not express SIRT3 are characterized by increased poor cellular differentiation, increased diffuse-type Lauren’s histology, and increases scirrhous-type stromal reactions, suggesting the SIRT3 functions as a tumor suppressor.

Are YOU the Smartest Doc in America?

The Smartest Doc from MDLinx keeps you current with a competitive edge, pitting colleagues against one other for the title of The Smartest Doc in America.

Take the Challenge

Clinical Pearls

Clinical Pearl from Smartest DocScreen-detected children with celiac disease can attain satisfactory dietary adherence and benefit from treatment similarly to symptom-detected patients.

Clinical Pearl from Smartest DocIntraoperative cholangiography using indocyanine green may be effective for the detection of extrahepatic ducts.

Clinical Pearl from Smartest DocFlexible sigmoidoscopy plus fecal occult blood testing reduce the incidence and mortality of colorectal cancer.

Be Ready for Upcoming 2015 Board Exams!

Be prepared for board reviews with confidence with 1000s of board exam style questions. Prepare Here