The Latest Journal Articles in Gastroenterology

1Loss of infliximab into feces is associated with lack of response to therapy in patients with severe ulcerative colitisGastroenterology, May 01, 2015  Clinical Article
2Systematic review with meta-analysis: Comparison between therapeutic regimens for paediatric chronic hepatitis CAlimentary Pharmacology and Therapeutics, May 01, 2015  Evidence Based Medicine  Review Article
3A randomized, placebo-controlled trial of lubiprostone for opioid-induced constipation in chronic noncancer pain The American Journal of Gastroenterology, May 01, 2015  Clinical Article
4Capecitabine and irinotecan with bevacizumab 2-weekly for metastatic colorectal cancer: the phase II AVAXIRI studyBMC Cancer, May 01, 2015  Full Text  Clinical Article
5A systematic review and meta-analysis of the n-3 polyunsaturated fatty acids effects on inflammatory markers in colorectal cancerClinical Nutrition, May 01, 2015  Evidence Based Medicine  Review Article
6Sorafenib treatment in Child-Pugh A and B patients with advanced hepatocellular carcinoma: safety, efficacy and prognostic factorsInvestigational New Drugs, May 01, 2015  Clinical Article
7Chronic recurrent multifocal osteomyelitis and inflammatory bowel diseaseJournal of Pediatric Gastroenterology and Nutrition, May 01, 2015  Clinical Article
8Lack of a clinically significant impact of race on morbidity and mortality in abdominal surgery: an analysis of 186,466 patients from the ACS NSQIP DatabaseThe American Journal of Surgery, May 01, 2015  Clinical Article
9Long-term outcomes after elective ileocecal resection in children with active localized Crohn's disease--a multicenter European studyJournal of Pediatric Surgery, May 01, 2015  Clinical Article
10Incidence and patterns of late recurrences in colon cancer patientsInternational Journal of Cancer, May 01, 2015  Clinical Article
1Notes from the field: Campylobacteriosis outbreak associated with consuming undercooked chicken liver pate - Ohio and Oregon, December 2013-January 2014Morbidity and Mortality Weekly Report, May 01, 2015
2Why do obese men get bariatric surgery far less than women?UC San Diego Health System, May 01, 2015
3Inflammatory bowel disease: A gut bacterium with beneficial propertiesInserm (Institut national de la santé et de la recherche médicale), May 01, 2015
4Fine mapping of MHC region leads to identification of new genetic risk factors for celiac diseaseBroad Institute News, May 01, 2015
5Two-thirds of bowel cancer patients aren't advised to exercise despite health benefitsCancer Research UK News, May 01, 2015
6Metformin use may not improve pancreatic cancer survivalAmerican Association for Cancer Research News, April 30, 2015
7Joslin researchers find gastric band and weight management therapies offer similar health benefits for overweight diabetes patientsJoslin Diabetes Center News, April 30, 2015
8Novel mechanism for Crohn’s disease uncoveredTechnische Universität München, April 30, 2015
9Genital-only screening misses many cases of gonorrhea and chlamydia in womenJohns Hopkins Medicine, April 29, 2015
10Identified a novel therapeutic target for type of colorectal cancer with poor prognosisIDIBELL-Bellvitge Biomedical Research Institute News, April 29, 2015

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Decreased PTPN12 expression associated with poor prognosis in HCC

As reported in PLoS ONE, the expression of PTPN12 was decreased in hepatocellular carcinoma tissue samples compared with adjacent normal tissues. Furthermore, decreased PTPN12 expression was associated with tumor recurrence, decreased cancer-specific survival, and decreased recurrence-free survival.

Predictors of sustained binge drinking

As reported in Alcoholism: Clinical & Experimental Research, sustained binge drinkers have an earlier onset, drink monthly in secondary school, binged in their 20s, exhibit impulsivity and novelty-seeking, and have depressive symptoms during adolescence compared to those who stop binge drinking.

SCCA-IgM predicts survival in HCC patients

As reported in the Journal of Gastroenterology & Hepatology, SCCA-IgM levels are elevated in patients with hepatocellular carcinoma (HCC) compared to patients with cirrhosis and healthy controls. Not only does the SCCA-IgM level predict overall and progression-free survival in HCC patients, but the sensitivity of SCCA-IgM in patients with HCC was 2-fold greater than AFP. A decline in SCCA-IgM levels was shown to be associated with response to treatment.

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Clinical Pearl from Smartest DocHBV-Infektionen stellen keinen Risikofaktor für Pankreas- oder hepatozelluläre Karzinome dar.

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Clinical Pearl from Smartest DocSurgery for solid pseudopapillary tumor of the pancreas in children should involve radical resection with negative margins.

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