Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Combination therapy with an immunomodulator and anti-TNFα agent improves bone mineral density in IBD patients Journal of Crohn's and Colitis, October 31, 2014    Clinical Article

2 Inverse association between coffee consumption and risk of cholecystectomy in women but not in men Clinical Gastroenterology and Hepatology , October 31, 2014    Clinical Article

3 Variation among US hospitals in inpatient mortality for cirrhosis Clinical Gastroenterology and Hepatology , October 31, 2014    Clinical Article

4 Membrane-bound mucins and mucin terminal glycans expression in idiopathic or Helicobacter pylori, NSAID associated peptic ulcers Full Text World Journal of Gastroenterology, October 31, 2014    Clinical Article

5 Effects of antiviral therapy for patients with inflammatory bowel disease and a positive intestinal biopsy for cytomegalovirus Clinical Gastroenterology and Hepatology , October 31, 2014    Clinical Article

6 Increased survival for patients with cirrhosis and organ failure in liver intensive care and validation of the chronic liver failure–sequential organ failure scoring system Clinical Gastroenterology and Hepatology , October 31, 2014    Clinical Article

7 Epidemiology of hepatitis C in Europe Digestive and Liver Diseases, October 31, 2014    Review Article

8 Overt and occult hepatitis B virus infection in adult Sudanese HIV patients International Journal of Infectious Diseases, October 31, 2014    Clinical Article

9 Suppressive effect of interleukin 10 on priming of naive hepatitis C virus-specific CD8+ T cells The Journal of Infectious Diseases, October 31, 2014    Clinical Article

10 A phase II, open-label, multicenter study to evaluate the antitumor efficacy of CO-1.01 as second-line therapy for gemcitabine-refractory patients with stage IV pancreatic adenocarcinoma and negative tumor hENT1 expression Pancreatology, October 31, 2014    Clinical Article

11 Rifaximin: a review of its use in reducing recurrence of overt hepatic encephalopathy episodes Drugs, October 31, 2014    Review Article

12 Conization as a marker of persistent cervical human papillomavirus (HPV) infection and risk of gastrointestinal cancer: A Danish 34-year nationwide cohort study Cancer Causes and Control, October 31, 2014    Clinical Article

13 Diagnostic performance of EUS in predicting advanced cancer among patients with Barrett’s esophagus and high-grade dysplasia/early adenocarcinoma: systemic review and meta-analysis Gastrointestinal Endoscopy, October 31, 2014    Evidence Based Medicine    Review Article

14 Chemotherapy-related reactivation of hepatitis B infection: Updates in 2013 Full Text World Journal of Gastroenterology, October 31, 2014    Review Article

15 Effect of gastrectomy with bursectomy on prognosis of gastric cancer: A meta-analysis Full Text World Journal of Gastroenterology, October 31, 2014    Evidence Based Medicine

16 Cost-effectiveness of telaprevir in patients with genotype 1 hepatitis C in Australia Value in Health, October 31, 2014    Clinical Article

17 Actively using clopidogrel correlates with increased risk of acute pancreatitis in Taiwan International Journal of Cardiology, October 31, 2014    Clinical Article

18 Emergence of multidrug resistant infection in patients with severe acute pancreatitis Pancreatology, October 31, 2014    Clinical Article

19 Laparoscopic versus open liver resection for metastatic colorectal cancer: A metaanalysis of 610 patients Surgery, October 31, 2014    Clinical Article

20 Non-occlusive mesenteric ischaemia: The prevalent cause of gastrointestinal infarction in patients with severe burn injuries Injury, October 31, 2014    Clinical Article

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Highlights in Gastroenterology

KIT mutations associated with poor prognosis in GISTs

Based on a meta-analysis (18 studies; n=1487) reported in the World Journal of Surgical Oncology, KIT mutations in patients with gastrointestinal stromal tumors (GISTs) are associated with larger tumors (> 5 cm), higher mitotic activity (> 5), more frequent recurrences (OR = 2.06), more frequent metastases (OR = 2.77), and worse 3-year overall survival (OR = 0.47) compared to patients with PDGFRA mutations or wild-type.

Infliximab is effective in corticosteroid-refractory ulcerative colitis

As reported in the Journal of Crohn’s & Colitis, treatment of corticosteroid-refractory ulcerative colitis patients with 3 doses of infliximab (n=113) resulted in short- (3 months) and long-term (12 months) colectomy rates of 18.6% and 25.6%, respectively. The RR of colectomy in patients with an elevated CRP and severe endoscopic lesions was 2.15 and 5.13, respectively.

Calcium reduces CRC risk

As reported in the International Journal of Cancer, there is an 8% reduction in CRC risk with each 300 mg/d increase in calcium intake based on 15 studies involving 12305 patients who took 250-1900 mg of calcium/day over a 3.3-16 year follow-up period. The beneficial effect extended beyond 1000 mg/d.

Other Topics in Gastroenterology

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