Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

1 Health-related self-perceptions over time and provider-based Complementary and Alternative Medicine (CAM) use in people with inflammatory bowel disease or arthritis Complementary Therapies in Medicine, September 29, 2014    Clinical Article

2 Indicators of sorafenib efficacy in patients with advanced hepatocellular carcinoma Full Text World Journal of Gastroenterology, September 29, 2014    Clinical Article

3 Relation between eosinophilic esophagitis and oral immunotherapy for food allergy: a systematic review with meta-analysis Annals of Allergy, Asthma, and Immunology, September 29, 2014    Evidence Based Medicine    Review Article

4 Measures of adiposity are associated with increased risk of peptic ulcer Clinical Gastroenterology and Hepatology , September 29, 2014    Review Article

5 Nonsteroidal anti-inflammatory drugs and the risk of Barrett's esophagus Clinical Gastroenterology and Hepatology , September 29, 2014    Clinical Article

6 Characterization of corticobulbar pharyngeal neurophysiology in dysphagic patients with Parkinson's disease Clinical Gastroenterology and Hepatology , September 29, 2014    Clinical Article

7 Increasing participation in colorectal cancer screening: Results from a cluster randomized trial of directly mailed gFOBT kits to previous nonresponders International Journal of Cancer, September 29, 2014    Clinical Article

8 A sonographic lesion index for Crohn's disease helps monitor changes in transmural bowel damage during therapy Clinical Gastroenterology and Hepatology , September 29, 2014    Clinical Article

9 Fighting an uphill battle: Experience with the HCV triple therapy: A qualitative thematic analysis Full Text BMC Infectious Diseases, September 29, 2014    Clinical Article

10 Citalopram for pediatric functional abdominal pain: a randomized, placebo-controlled trial Neurogastroenterology & Motility, September 29, 2014    Clinical Article

11 No evidence of gene-calcium interactions from genome-wide analysis of colorectal cancer risk Cancer Epidemiology, Biomarkers & Prevention, September 29, 2014

12 Skewed B cells in chronic hepatitis C virus infection maintain their ability to respond to virus-induced activation Journal of Viral Hepatitis, September 29, 2014    Clinical Article

13 Occupational exposures and colorectal cancers: A quantitative overview of epidemiological evidence Full Text World Journal of Gastroenterology, September 29, 2014    Evidence Based Medicine

14 A pooled analysis of body mass index and pancreatic cancer mortality in African Americans Cancer Epidemiology, Biomarkers & Prevention, September 29, 2014    Clinical Article

15 Effect of low serum total bilirubin levels (≤0.32 mg/dl) on risk of coronary artery disease in patients with metabolic syndrome The American Journal of Cardiology, September 29, 2014    Clinical Article

16 Helicobacter pylori induces vascular endothelial growth factor production in gastric epithelial cells through hypoxia-inducible factor-1α-dependent pathway Helicobacter, September 29, 2014    Clinical Article

17 Serum immunoglobulin A concentration is a reliable biomarker for liver fibrosis in non-alcoholic fatty liver disease Full Text World Journal of Gastroenterology, September 29, 2014    Clinical Article

18 Volumetric fat ratio and not body mass index is predictive of ileocolectomy outcomes in Crohn's disease patients Digestive Surgery, September 29, 2014    Clinical Article

19 Successful surgical strategy in a late case of Boerhaave’s syndrome Full Text World Journal of Gastroenterology, September 29, 2014    Clinical Article

20 Reduced insulin-like growth factor I receptor and altered insulin receptor isoform mRNAs in normal mucosa predict colorectal adenoma risk Cancer Epidemiology, Biomarkers & Prevention, September 29, 2014    Clinical Article

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Highlights in Gastroenterology

KIT mutations associated with poor prognosis in GISTs

Based on a meta-analysis (18 studies; n=1487) reported in the World Journal of Surgical Oncology, KIT mutations in patients with gastrointestinal stromal tumors (GISTs) are associated with larger tumors (> 5 cm), higher mitotic activity (> 5), more frequent recurrences (OR = 2.06), more frequent metastases (OR = 2.77), and worse 3-year overall survival (OR = 0.47) compared to patients with PDGFRA mutations or wild-type.

Infliximab is effective in corticosteroid-refractory ulcerative colitis

As reported in the Journal of Crohn’s & Colitis, treatment of corticosteroid-refractory ulcerative colitis patients with 3 doses of infliximab (n=113) resulted in short- (3 months) and long-term (12 months) colectomy rates of 18.6% and 25.6%, respectively. The RR of colectomy in patients with an elevated CRP and severe endoscopic lesions was 2.15 and 5.13, respectively.

Decreased PTPN12 expression associated with poor prognosis in HCC

As reported in PLoS ONE, the expression of PTPN12 was decreased in hepatocellular carcinoma tissue samples compared with adjacent normal tissues. Furthermore, decreased PTPN12 expression was associated with tumor recurrence, decreased cancer-specific survival, and decreased recurrence-free survival.


Other Topics in Gastroenterology

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