Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Cumulative incidence of second intestinal resection in Crohn's disease: A systematic review and meta-analysis of population-based studies The American Journal of Gastroenterology, October 24, 2014    Evidence Based Medicine    Review Article

2 Effects of N-3 fish oil on metabolic and histological parameters in NASH: A double-blind, randomized, placebo-controlled trial Journal of Hepatology, October 24, 2014    Clinical Article

3 Species-specific engagement of human NOD2 and TLR signaling upon intracellular bacterial infection: Role of Crohn's associated NOD2 gene variants Clinical and Experimental Immunology, October 24, 2014    Clinical Article

4 Therapeutic management and outcome of locoregional recurrence after curative colorectal cancer therapy--a single-center analysis Journal of Gastrointestinal Surgery, October 24, 2014    Clinical Article

5 Factors associated with progression to surgery in Crohn's disease patients with endoscopic stricture Endoscopy, October 24, 2014    Clinical Article

6 Vitamin D prevents the intestinal fibrosis via induction of vitamin D receptor and inhibition of transforming growth factor-beta1/Smad3 pathway Digestive Diseases and Sciences, October 24, 2014    Clinical Article

7 Positive outcomes with negative pressure therapy over primarily closed large abdominal wall reconstruction reduces surgical site infection rates Hernia, October 24, 2014    Clinical Article

8 New therapies for primary biliary cirrhosis Clinical Reviews in Allergy and Immunology, October 24, 2014    Clinical Article

9 Impact of alcohol consumption on survival in patients with esophageal carcinoma: a large cohort with long-term follow-up Cancer Science, October 24, 2014    Clinical Article

10 Prospective evaluation of the impact of sonography on the management and surgical intervention of neonates with necrotizing enterocolitis Pediatric Surgery International, October 24, 2014    Clinical Article

11 Quality of life after acute pancreatitis: A systematic review and meta-analysis Pancreas, October 24, 2014    Evidence Based Medicine    Review Article

12 HER2 amplification detected in the circulating DNA of patients with gastric cancer: A retrospective pilot study Gastric Cancer, October 24, 2014    Clinical Article

13 Photodynamic therapy using nanoparticle loaded with indocyanine green for experimental peritoneal dissemination of gastric cancer Cancer Science, October 24, 2014    Clinical Article

14 The incidence of esophageal adenocarcinoma in a national veterans cohort with Barrett’s esophagus The American Journal of Gastroenterology, October 24, 2014    Clinical Article

15 Normal weight diabetic patients versus obese diabetics: relation of overall and abdominal adiposity to vascular health Full Text Cardiovascular Diabetology, October 24, 2014    Clinical Article

16 ANGPTL2 renders colorectal cancer cells resistant to chemotherapy by activating Syk-PI3K-dependent anti-apoptotic signaling Cancer Science, October 24, 2014    Clinical Article

17 Prediction of late distant recurrence after 5 years of endocrine treatment: A combined analysis of patients from the Austrian Breast and Colorectal Cancer Study Group 8 and arimidex, tamoxifen alone or in combination randomized trials using the PAM50 risk of recurrence score Journal of Clinical Oncology, October 24, 2014    Clinical Article

18 Ontogeny of intestinal epithelial innate immune responses Frontiers in Immunology, October 24, 2014    Review Article

19 Systems biological analyses reveal the HCV-specific regulation of hematopoietic development Hepatology, October 24, 2014    Clinical Article

20 Cost-effectiveness analysis of sofosbuvir-based regimens for chronic hepatitis C Gut, October 24, 2014    Clinical Article

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Highlights in Gastroenterology

Elevated ?-GT predicts HCC in hepatitis C patients with sustained response

As reported in the Journal of Hepatology, an elevated baseline ɣ-GT level is the strongest predictor of developing HCC in non-cirrhotic patients with hepatitis C and a sustained virologic response (HR = 6.44), followed by age (HR = 3.68).

Increased MMP-9 expression associated with poor prognosis in CRC

As reported in the World Journal of Surgical Oncology, the expression of MMP-9 in colon cancer tissues was increased compared to distal normal mucosa (69.1% vs. 2.9%). Increased MMP-9 expression was associated with lymph node metastasis, Duke stage, and decreased survival.

SCCA-IgM predicts survival in HCC patients

As reported in the Journal of Gastroenterology & Hepatology, SCCA-IgM levels are elevated in patients with hepatocellular carcinoma (HCC) compared to patients with cirrhosis and healthy controls. Not only does the SCCA-IgM level predict overall and progression-free survival in HCC patients, but the sensitivity of SCCA-IgM in patients with HCC was 2-fold greater than AFP. A decline in SCCA-IgM levels was shown to be associated with response to treatment.

Other Topics in Gastroenterology

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