Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

1 The therapeutic potential of carbon monoxide for inflammatory bowel disease Digestion, January 30, 2015    Review Article

2 Diet and colorectal cancer Maturitas, January 30, 2015    Review Article

3 New aspects in the pathomechanism and diagnosis of the laryngopharyngeal reflux-clinical impact of laryngeal proton pumps and pharyngeal pH metry in extraesophageal gastroesophageal reflux disease Full Text World Journal of Gastroenterology, January 30, 2015    Clinical Article

4 Long-term follow-up of successful hepatitis C virus therapy: waning immune responses and disappearance of liver disease are consistent with cure Alimentary Pharmacology and Therapeutics, January 30, 2015    Clinical Article

5 Prolonged Clostridium difficile infection may be associated with vitamin D deficiency Journal of Parenteral and Enteral Nutrition, January 30, 2015    Review Article

6 Malnutrition assessed through phase angle and its relation to prognosis in patients with compensated liver cirrhosis: A prospective cohort study Digestive and Liver Diseases, January 30, 2015    Clinical Article

7 Visits to primary care physicians among persons who inject drugs at high risk of hepatitis C virus infection: Room for improvement Journal of Viral Hepatitis, January 30, 2015    Clinical Article

8 Centralized isolation of Helicobacter pylori from multiple centers and transport condition influences Full Text World Journal of Gastroenterology, January 30, 2015    Clinical Article

9 Randomized controlled trial of low-volume bowel preparation agents for colonic bowel preparation: 2-L polyethylene glycol with ascorbic acid versus sodium picosulfate with magnesium citrate International Journal of Colorectal Disease, January 30, 2015    Clinical Article
Exclusive Author Commentary

10 Population-based Lynch Syndrome screening by microsatellite instability in patients ≤50: prevalence, testing determinants, and result availability prior to colon surgery The American Journal of Gastroenterology, January 30, 2015    Clinical Article

11 Contrast-enhanced ultrasound in the diagnosis of patients suspected of having active Crohn's disease: meta-analysis Ultrasound in Medicine and Biology, January 30, 2015    Evidence Based Medicine   Review Article

12 Impact of age and medical comorbidity on adjuvant treatment outcomes for stage III colon cancer: A pooled analysis of individual patient data from four randomized controlled trials Annals of Oncology, January 30, 2015    Clinical Article

13 Salmonella-induced diarrhea occurs in the absence of IL-8 receptor (CXCR2)-dependent neutrophilic inflammation The Journal of Infectious Diseases, January 30, 2015    Clinical Article

14 Inhibiting protein arginine deiminases has anti-oxidant consequences Journal of Pharmacology and Experimental Therapeutics, January 30, 2015    Clinical Article

15 Supraesophageal reflux: correlation of position and occurrence of acid reflux; effect of head-of-bed elevation on supine reflux The Journal of Allergy and Clinical Immunology: In Practice, January 30, 2015    Clinical Article

16 Genetic association of apolipoprotein E polymorphisms with inflammatory bowel disease Full Text World Journal of Gastroenterology, January 30, 2015    Clinical Article

17 Prognosis after resection for hepatitis B virus-associated intrahepatic cholangiocarcinoma Full Text World Journal of Gastroenterology, January 30, 2015    Clinical Article

18 Albumin and magnetic resonance imaging-liver volume to identify hepatitis B-related cirrhosis and esophageal varices Full Text World Journal of Gastroenterology, January 30, 2015    Clinical Article

19 Characteristics and factors related to quality of life in Mexican Mestizo patients with celiac disease Full Text BMC Gastroenterology, January 30, 2015    Clinical Article

20 Prevalence of the hepatitis C virus NS3 polymorphism Q80K in genotype 1 patients in the European region Antiviral Research , January 30, 2015    Clinical Article

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Highlights in Gastroenterology

Increased MMP-9 expression associated with poor prognosis in CRC

As reported in the World Journal of Surgical Oncology, the expression of MMP-9 in colon cancer tissues was increased compared to distal normal mucosa (69.1% vs. 2.9%). Increased MMP-9 expression was associated with lymph node metastasis, Duke stage, and decreased survival.

SIRT3 expression improves prognosis in gastric cancer

As reported in the World Journal of Surgery, SIRT3 expression improves the prognosis in patients with gastric cancer (n=221). Specifically, the 5-year OS was 51.2% and 39.1% in patients who do and do not express SIRT3, respectively. The 5-year DFS was 49.6% and 38.0% in patients who do and do not express SIRT3, respectively. Patients who do not express SIRT3 are characterized by increased poor cellular differentiation, increased diffuse-type Lauren’s histology, and increases scirrhous-type stromal reactions, suggesting the SIRT3 functions as a tumor suppressor.

SCCA-IgM predicts survival in HCC patients

As reported in the Journal of Gastroenterology & Hepatology, SCCA-IgM levels are elevated in patients with hepatocellular carcinoma (HCC) compared to patients with cirrhosis and healthy controls. Not only does the SCCA-IgM level predict overall and progression-free survival in HCC patients, but the sensitivity of SCCA-IgM in patients with HCC was 2-fold greater than AFP. A decline in SCCA-IgM levels was shown to be associated with response to treatment.


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