Hepatitis C

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We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Statin use reduces risk of esophageal adenocarcinoma in US veterans with Barrett’s esophagus: A Nested case–control studyGastroenterology, July 28, 2015  Clinical Article
2The role of aspirin, vitamin D, exercise, diet, statins, and metformin in the prevention and treatment of colorectal cancerCurrent Treatment Options in Oncology, July 28, 2015  Review Article
3Association of hepatocyte-derived growth factor receptor/caudal type homeobox 2 co-expression with mucosal regeneration in active ulcerative colitisWorld Journal of Gastroenterology, July 28, 2015  Full Text  Clinical Article
4Impact of switching from mycophenolate mofetil to enteric-coated mycophenolate sodium on gastrointestinal side effects in patients with autoimmune disease: a Phase III, open-label, single-arm, multicenter studyClinical and Experimental Gastroenterology, July 28, 2015  Full Text  Clinical Article
5Outcome of adefovir add-on lamivudine rescue therapy of up to 5 years in patients with lamivudine-resistant chronic hepatitis BJournal of Gastroenterology and Hepatology, July 28, 2015  Review Article
6A phase II study of S-1, oxaliplatin, oral leucovorin, and bevacizumab combination therapy (SOLA) in patients with unresectable metastatic colorectal cancerCancer Chemotherapy and Pharmacology, July 28, 2015  Clinical Article
7Efficacy of 4 years of octreotide long-acting release therapy in patients with severe polycystic liver diseaseMayo Clinic Proceedings, July 28, 2015  Clinical Article
8HCV infection is associated with lower survival in simultaneous liver kidney transplant recipients in the U.SClinical Transplantation, July 28, 2015  Clinical Article
9Serologic assay for diagnosis of celiac disease based on a patient-derived monoclonal anti-gliadin antibodyGastroenterology, July 28, 2015  Clinical Article
10Online combination algorithm for non-invasive assessment of chronic hepatitis B related liver fibrosis and cirrhosis in resource-limited settingsEuropean Journal of Internal Medicine , July 28, 2015  Clinical Article

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We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Soybean oil causes more obesity than coconut oil and fructoseThe University of California, Riverside Health News, July 28, 2015
2Study shows targeting bacteria causing ulcers may prevent stomach cancerMcMaster University Faculty of Health Sciences News, July 28, 2015
3Launch of a nationwide hepatitis C elimination program - Georgia, April 2015Morbidity and Mortality Weekly Report, July 28, 2015
4Viral hepatitis surveillance - India, 2011-2013Morbidity and Mortality Weekly Report, July 28, 2015
5Gene variants increase colorectal cancer risk, study showsUW Medicine, July 28, 2015
6New material opens possibilities for super-long-acting pillsMassachusetts Institute of Technology Research News, July 28, 2015
7Study: Many consumers do not wash their hands after cracking eggs, increasing food poisoning riskRTI International News, July 27, 2015
8New 'chemotherapy booster' could treat lung and pancreatic cancerInstitute of Cancer Research, July 27, 2015
9FDA approves new treatment for chronic hepatitis C genotype 3 infectionsFDA Press Announcements, July 27, 2015
10FDA approves Technivie for treatment of chronic hepatitis C genotype 4FDA Press Announcements, July 27, 2015

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Risk factors for CHC-related death identified

As reported in the World Journal of Gastroenterology, the following risk factors for chronic hepatitis C (CHC)-related deaths have been identified (n=8250 CHC patients; n=144 CHC-related deaths): α-IFN therapy (AOR=0.53); liver cirrhosis (AOR=2.89); hepatocellular carcinoma versus CHC (AOR=8.82); hypertension (AOR=1.76); alcohol consumption (AOR=1.73); and HBsAg positivity (AOR=22.28).

SIRT3 expression improves prognosis in gastric cancer

As reported in the World Journal of Surgery, SIRT3 expression improves the prognosis in patients with gastric cancer (n=221). Specifically, the 5-year OS was 51.2% and 39.1% in patients who do and do not express SIRT3, respectively. The 5-year DFS was 49.6% and 38.0% in patients who do and do not express SIRT3, respectively. Patients who do not express SIRT3 are characterized by increased poor cellular differentiation, increased diffuse-type Lauren’s histology, and increases scirrhous-type stromal reactions, suggesting the SIRT3 functions as a tumor suppressor.

SCCA-IgM predicts survival in HCC patients

As reported in the Journal of Gastroenterology & Hepatology, SCCA-IgM levels are elevated in patients with hepatocellular carcinoma (HCC) compared to patients with cirrhosis and healthy controls. Not only does the SCCA-IgM level predict overall and progression-free survival in HCC patients, but the sensitivity of SCCA-IgM in patients with HCC was 2-fold greater than AFP. A decline in SCCA-IgM levels was shown to be associated with response to treatment.

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Clinical Pearl from Smartest DocMicroRNAs are known as translational regulators of tumor suppressor or oncogenes.

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Clinical Pearl from Smartest DocAge, ALT and HBV DNA levels, and HBV variants may predict a significant risk of fibrosis in chronic hepatitis B patients.

Clinical Articles in Gastroenterology

MDLinx Gastroenterology and HepatologyNews

Search today's latest gastroenterology news, updated daily from over 2,000 peer-reviewed journals, at MDLinx. Stay current with up-to-the-minute digestive system information and hepatology related clinical research covering all aspects of the gastrointestinal (GI) tract. Our diligent team of MDLinx physician editors rigorously research a wide range of gastroenterology medical journals dedicated to biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition and diagnostic imaging. They then summarize and rank the articles by clinical impact to provide the most valuable literature to make sure any gastroenterologist, and all members of their healthcare team, can stay current with the latest in gastrointestinal clinical research and hepatobiliary medicine.

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