The Latest Clinical Articles in Gastroenterology & GastroIntestinal

1Obesity in inflammatory bowel disease Digestive Diseases and Sciences, April 01, 2015  Review Article
2Early life body fatness and risk of colorectal cancer in U.S. women and men—results from two large cohort studiesCancer Epidemiology, Biomarkers & Prevention, April 01, 2015  Clinical Article
3Association of cholesterol with risk of pancreatic cancer: A meta-analysisWorld Journal of Gastroenterology, April 01, 2015  Full Text  Clinical Article
4Impact of metabolic syndrome on the hospitalization rate of Crohn's disease patients seen at a tertiary care center: A retrospective cohort studyDigestion, April 01, 2015  Clinical Article
5Open-label phase 1b study of FOLFIRI plus cetuximab plus IMO-2055 in patients with colorectal cancer who have progressed following chemotherapy for advanced or metastatic diseaseCancer Chemotherapy and Pharmacology, April 01, 2015  Clinical Article
6Helicobacter pylori infection in psoriasis: Results of a clinical study and review of the literatureInternational Journal of Dermatology, April 01, 2015  Clinical Article  Review Article
7Brain metastasis from colorectal carcinomaIrish Journal of Medical Science, April 01, 2015  Clinical Article
8Long-term efficacy of biofeedback therapy in patients with dyssynergic defecation: Results of a median 44 months follow-upNeurogastroenterology & Motility, April 01, 2015  Clinical Article
9Phase II study of gemcitabine and S-1 combination chemotherapy in patients with metastatic biliary tract cancerCancer Chemotherapy and Pharmacology, April 01, 2015  Clinical Article
10Quantitative assessment of small bowel motility in patients with Crohn's disease using dynamic MRINeurogastroenterology & Motility, April 01, 2015  Clinical Article
1UCLA researchers develop more accurate tool to predict whether liver cancer will recur in transplant patientsUCLA Health System, April 01, 2015
2Eat your veggies to lower colon cancer riskBaylor Health Care System, April 01, 2015
3University Hospitals Leuven successfully apply innovative technique for liver transplantsKU Leuven News, April 01, 2015
4Protein may improve liver regenerationUC Davis Health System, April 01, 2015
5Genetic background determines whether aspirin/NSAIDS will reduce colorectal cancer riskMassachusetts General Hospital, March 31, 2015
6Drinking raw milk dramatically increases risk for foodborne illness, analysis findsJohns Hopkins Bloomberg School of Public Health, March 31, 2015
7ASCP, CAP, AMP, and ASCO issue draft colorectal cancer molecular marker testing guideline and announce opening of public comment periodAmerican Society of Clinical Oncology (ASCO) News, March 31, 2015
8FDA warns against combination of hepatitis C treatment and antiarrhythmic drugAmerican College of Cardiology News, March 31, 2015
9MAIT cell alterations involved in obesity and T2 diabetesCentre National de la Recherche Scientifique News, March 31, 2015
10Researchers reverse type 2 diabetes and fatty liver diseaseUniversity of Copenhagen Faculty of Health and Medical Sciences News, March 30, 2015

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Risk factors for CHC-related death identified

As reported in the World Journal of Gastroenterology, the following risk factors for chronic hepatitis C (CHC)-related deaths have been identified (n=8250 CHC patients; n=144 CHC-related deaths): α-IFN therapy (AOR=0.53); liver cirrhosis (AOR=2.89); hepatocellular carcinoma versus CHC (AOR=8.82); hypertension (AOR=1.76); alcohol consumption (AOR=1.73); and HBsAg positivity (AOR=22.28).

Risk factors for intra-abdominal abscesses in Crohn’s disease

As reported in Digestion, uncontrolled CRP at week 14 of therapy with infliximab (OR=1.36) and early loss of response to infliximab (OR=5.36) are independent risk factors for intra-abdominal abscesses in patients with Crohn’s disease.

Predictors of sustained binge drinking

As reported in Alcoholism: Clinical & Experimental Research, sustained binge drinkers have an earlier onset, drink monthly in secondary school, binged in their 20s, exhibit impulsivity and novelty-seeking, and have depressive symptoms during adolescence compared to those who stop binge drinking.

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