Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Adalimumab drug and antibody levels as predictors of clinical and laboratory response in patients with Crohn's disease Alimentary Pharmacology and Therapeutics, July 28, 2014    Clinical Article

2 Isotretinoin use and celiac disease: A population-based cross-sectional study American Journal of Clinical Dermatology, July 28, 2014    Clinical Article

3 Incidence of malignancies in diagnosed celiac patients: a population-based estimate The American Journal of Gastroenterology, July 28, 2014    Clinical Article

4 The pharmacokinetics, pharmacodynamics and safety of oral doses of ilaprazole 10, 20 and 40 mg and esomeprazole 40 mg in healthy subjects: A randomised, open-label crossover study Alimentary Pharmacology and Therapeutics, July 28, 2014    Clinical Article

5 Predictors of either rapid healing or refractory reflux oesophagitis during treatment with potent acid suppression Alimentary Pharmacology and Therapeutics, July 28, 2014    Clinical Article

6 Diabetes, antidiabetic medications and pancreatic cancer risk: an analysis from the international pancreatic cancer case-control consortium Annals of Oncology, July 28, 2014    Clinical Article

7 Kinetics of hepatitis B surface antigen loss in patients with HBeAg-positive chronic hepatitis B treated with tenofovir disoproxil fumarate Journal of Hepatology, July 28, 2014    Clinical Article

8 Golimumab in unresponsive ulcerative colitis Full Text Biologics: targets & therapy, July 28, 2014    Review Article

9 Interferon {gamma}-induced protein10 kinetics in treatment-naive versus treatment-experienced patients receiving interferon-free therapy for hepatitis C virus infection: Implications for the innate immune response The Journal of Infectious Diseases, July 28, 2014    Clinical Article

10 Primary sclerosing cholangitis as an independent risk factor for colorectal cancer in the context of inflammatory bowel disease: A review of the literature Full Text World Journal of Gastroenterology, July 28, 2014    Review Article

11 Yogurt consumption, weight change and risk of overweight/obesity: The SUN cohort study Nutrition, Metabolism & Cardiovascular Diseases, July 28, 2014    Clinical Article

12 The management of postoperative reflux in congenital esophageal atresia-tracheoesophageal fistula: A systematic review Pediatric Surgery International, July 28, 2014    Evidence Based Medicine    Review Article

13 Colorectal cancer outcome inequalities: association between population density, race, and socioeconomic status Full Text Rural and Remote Health, July 28, 2014    Clinical Article

14 Non-alcoholic fatty liver disease and type 2 diabetes mellitus: The liver disease of our age? Full Text World Journal of Gastroenterology, July 28, 2014    Clinical Article

15 Does intramesorectal excision for ulcerative colitis impact bowel and sexual function when compared to total mesorectal excision? The American Journal of Surgery, July 28, 2014    Clinical Article

16 Kinase genotype analysis of gastric gastrointestinal stromal tumor cytology samples using targeted next-generation sequencing Clinical Gastroenterology and Hepatology , July 28, 2014    Clinical Article

17 Recurrence and mortality among patients hospitalized for acute lower gastrointestinal bleeding Clinical Gastroenterology and Hepatology , July 28, 2014    Clinical Article

18 Time to screening in the systems of support to increase colorectal cancer screening trial Cancer Epidemiology, Biomarkers & Prevention, July 28, 2014    Clinical Article

19 Hepatitis B surface antigen levels during natural history of chronic hepatitis B: A Chinese perspective study Full Text World Journal of Gastroenterology, July 28, 2014    Clinical Article

20 Esophageal anastomotic strictures: outcomes of endoscopic dilation, risk of recurrence and refractory stenosis, and effect of foreign body removal Clinical Gastroenterology and Hepatology , July 28, 2014    Clinical Article

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Highlights in Gastroenterology

KIT mutations associated with poor prognosis in GISTs

Based on a meta-analysis (18 studies; n=1487) reported in the World Journal of Surgical Oncology, KIT mutations in patients with gastrointestinal stromal tumors (GISTs) are associated with larger tumors (> 5 cm), higher mitotic activity (> 5), more frequent recurrences (OR = 2.06), more frequent metastases (OR = 2.77), and worse 3-year overall survival (OR = 0.47) compared to patients with PDGFRA mutations or wild-type.

Calcium reduces CRC risk

As reported in the International Journal of Cancer, there is an 8% reduction in CRC risk with each 300 mg/d increase in calcium intake based on 15 studies involving 12305 patients who took 250-1900 mg of calcium/day over a 3.3-16 year follow-up period. The beneficial effect extended beyond 1000 mg/d.

Decreased PTPN12 expression associated with poor prognosis in HCC

As reported in PLoS ONE, the expression of PTPN12 was decreased in hepatocellular carcinoma tissue samples compared with adjacent normal tissues. Furthermore, decreased PTPN12 expression was associated with tumor recurrence, decreased cancer-specific survival, and decreased recurrence-free survival.

Other Topics in Gastroenterology

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