Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Risk of peptic ulcer bleeding associated with Helicobacter pylori infection, NSAIDs, low-dose aspirin, and antihypertensive drugs: A case-control study Journal of Gastroenterology and Hepatology, October 23, 2014    Clinical Article

2 Validation of the estimation of physiologic ability and surgical stress (E-PASS) score for maintenance hemodialysis patients undergoing elective abdominal surgery Digestive Surgery, October 23, 2014    Review Article

3 Vitamin D level and sustained virologic response to interferon-based antiviral therapy in chronic hepatitis C: A systematic review and meta-analysis Journal of Hepatology, October 23, 2014    Review Article

4 The incidence of hepatocellular carcinoma is reduced in patients with chronic hepatitis B on long-term nucleos(t)ide analogue therapy Alimentary Pharmacology and Therapeutics, October 23, 2014    Clinical Article

5 Predictive factors for endoscopic visibility and strategies for pre-endoscopic prokinetics use in patients with upper gastrointestinal bleeding Digestive Diseases and Sciences, October 23, 2014    Clinical Article

6 Efficacy of Anti-RON antibody Zt/g4-drug maytansinoid conjugation (Anti-RON ADC) as a novel therapeutics for targeted colorectal cancer therapy Clinical Cancer Research, October 23, 2014    Clinical Article

7 The diagnosis of inflammatory bowel disease is often unsupported in clinical practice Digestive and Liver Diseases, October 23, 2014    Clinical Article

8 Effect of netazepide, a gastrin/CCK2 receptor antagonist, on gastric acid secretion and rabeprazole-induced hypergastrinaemia in healthy subjects British Journal of Clinical Pharmacology, October 23, 2014    Clinical Article

9 A novel approach to the diagnosis of pancreatic serous cystadenoma: needle-based confocal laser endomicroscopy Endoscopy, October 23, 2014    Review Article

10 Evaluation of a stool antigen test using a monoclonal antibody for native catalase for diagnosis of Helicobacter pylori infection in children and adults Journal of Medical Microbiology, October 23, 2014    Clinical Article

11 Magnetic resonance enterography in refractory iron deficiency anemia: A pictorial overview Full Text World Journal of Gastroenterology, October 23, 2014    Clinical Article

12 New perspectives in the assessment of future remnant liver Digestive Surgery, October 23, 2014    Clinical Article

13 Association between Wisteria floribunda agglutinin-positive Mac-2 binding protein and the fibrosis stage of non-alcoholic fatty liver disease Journal of Gastroenterology, October 23, 2014    Clinical Article

14 Efficacy and durability of robotic heller myotomy for achalasia: patient symptoms and satisfaction at long-term follow-up Surgical Endoscopy, October 23, 2014    Clinical Article

15 Optimal colorectal cancer screening in states low-income, uninsured populations--the case of South Carolina Health Services Research, October 23, 2014    Clinical Article

16 Hepatitis C viral proteins perturb metabolic liver zonation Journal of Hepatology, October 23, 2014    Clinical Article

17 Development and validation of a ‘capture-fusion’ model to study drug sensitivity of patient-derived hepatitis C Hepatology, October 23, 2014    Clinical Article

18 MiR-204-5p inhibits proliferation and invasion and enhances chemotherapeutic sensitivity of colorectal cancer cells by down-regulating RAB22A Clinical Cancer Research, October 23, 2014    Clinical Article

19 Prospective clinical trial of traction device-assisted endoscopic submucosal dissection of large superficial colorectal tumors using the S-O clip Surgical Endoscopy, October 23, 2014    Clinical Article

20 Reducing the neglected burden of viral hepatitis in Africa:Strategies for a global approach Journal of Hepatology, October 23, 2014    Review Article

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Highlights in Gastroenterology

Increased MMP-9 expression associated with poor prognosis in CRC

As reported in the World Journal of Surgical Oncology, the expression of MMP-9 in colon cancer tissues was increased compared to distal normal mucosa (69.1% vs. 2.9%). Increased MMP-9 expression was associated with lymph node metastasis, Duke stage, and decreased survival.

Elevated ?-GT predicts HCC in hepatitis C patients with sustained response

As reported in the Journal of Hepatology, an elevated baseline ɣ-GT level is the strongest predictor of developing HCC in non-cirrhotic patients with hepatitis C and a sustained virologic response (HR = 6.44), followed by age (HR = 3.68).

SIRT3 expression improves prognosis in gastric cancer

As reported in the World Journal of Surgery, SIRT3 expression improves the prognosis in patients with gastric cancer (n=221). Specifically, the 5-year OS was 51.2% and 39.1% in patients who do and do not express SIRT3, respectively. The 5-year DFS was 49.6% and 38.0% in patients who do and do not express SIRT3, respectively. Patients who do not express SIRT3 are characterized by increased poor cellular differentiation, increased diffuse-type Lauren’s histology, and increases scirrhous-type stromal reactions, suggesting the SIRT3 functions as a tumor suppressor.

Other Topics in Gastroenterology

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