Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature
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1 Levels of drug and antidrug antibodies are associated with outcome of interventions after loss of response to infliximab or adalimumab Clinical Gastroenterology and Hepatology , September 23, 2014    Clinical Article

2 Magnetic resonance enterography, small-intestine contrast US, and capsule endoscopy to evaluate the small bowel in pediatric Crohn’s disease: a prospective, blinded, comparison study Gastrointestinal Endoscopy, September 23, 2014    Clinical Article

3 A panel to predict long-term outcome of infliximab therapy for patients with ulcerative colitis Clinical Gastroenterology and Hepatology , September 23, 2014    Clinical Article

4 Outcomes of patients with chronic hepatitis B who do not meet criteria for antiviral treatment at presentation Clinical Gastroenterology and Hepatology , September 23, 2014    Review Article

5 Accuracy, safety, and tolerability of tissue collection by cytosponge vs endoscopy for evaluation of eosinophilic esophagitis Clinical Gastroenterology and Hepatology , September 23, 2014    Clinical Article

6 Effects of antidepressants in patients with functional esophageal disorders or gastroesophageal reflux disease: A systematic review Clinical Gastroenterology and Hepatology , September 23, 2014    Clinical Article

7 The association of peptic ulcer and schizophrenia: A population-based study Journal of Psychosomatic Research, September 23, 2014    Clinical Article

8 Prevalence of chronic narcotic use among children with inflammatory bowel disease Clinical Gastroenterology and Hepatology , September 23, 2014    Clinical Article

9 Use of endoscopic ultrasound in the preoperative staging of gastric cancer: A multi-institutional study of the U.S. gastric cancer collaborative Journal of the American College of Surgeons, September 23, 2014    Clinical Article

10 A rule for determining risk of colorectal cancer in patients with inflammatory bowel disease Clinical Gastroenterology and Hepatology , September 23, 2014    Clinical Article

11 Protection against gastroenteritis in US households with children who received rotavirus vaccine The Journal of Infectious Diseases, September 23, 2014    Clinical Article

12 Sacral nerve stimulation changes rectal sensitivity and biomechanical properties in patients with irritable bowel syndrome Neurogastroenterology & Motility, September 23, 2014    Clinical Article

13 Attachment and quality of life in patients with inflammatory bowel disease International Journal of Colorectal Disease, September 23, 2014    Clinical Article

14 Risk of upper gastrointestinal cancers in patients with gastroesophageal reflux disease after a negative screening endoscopy Clinical Gastroenterology and Hepatology , September 23, 2014    Clinical Article

15 High prevalence of inflammatory bowel disease in United States residents of Indian ancestry Clinical Gastroenterology and Hepatology , September 23, 2014    Clinical Article

16 Effects of obstructive sleep apnea on sleep quality, cognition, and driving performance in patients with cirrhosis Clinical Gastroenterology and Hepatology , September 23, 2014    Clinical Article

17 Survival benefit of repeat liver transplantation in the United States: A serial MELD analysis by hepatitis C status and donor risk index American Journal of Transplantation, September 23, 2014    Clinical Article

18 Effect of atorvastatin on pancreatic beta-cell function and insulin resistance in type 2 diabetes mellitus patients: a randomized pilot study Canadian Journal of Diabetes, September 23, 2014    Clinical Article

19 Clostridium colitis: challenges in diagnosis and treatment ANZ Journal of Surgery, September 23, 2014    Review Article

20 Uptake of hepatitis C specialist services and treatment following diagnosis by dried blood spot in Scotland Journal of Clinical Virology, September 23, 2014    Clinical Article

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Highlights in Gastroenterology

KIT mutations associated with poor prognosis in GISTs

Based on a meta-analysis (18 studies; n=1487) reported in the World Journal of Surgical Oncology, KIT mutations in patients with gastrointestinal stromal tumors (GISTs) are associated with larger tumors (> 5 cm), higher mitotic activity (> 5), more frequent recurrences (OR = 2.06), more frequent metastases (OR = 2.77), and worse 3-year overall survival (OR = 0.47) compared to patients with PDGFRA mutations or wild-type.

Calcium reduces CRC risk

As reported in the International Journal of Cancer, there is an 8% reduction in CRC risk with each 300 mg/d increase in calcium intake based on 15 studies involving 12305 patients who took 250-1900 mg of calcium/day over a 3.3-16 year follow-up period. The beneficial effect extended beyond 1000 mg/d.

SIRT3 expression improves prognosis in gastric cancer

As reported in the World Journal of Surgery, SIRT3 expression improves the prognosis in patients with gastric cancer (n=221). Specifically, the 5-year OS was 51.2% and 39.1% in patients who do and do not express SIRT3, respectively. The 5-year DFS was 49.6% and 38.0% in patients who do and do not express SIRT3, respectively. Patients who do not express SIRT3 are characterized by increased poor cellular differentiation, increased diffuse-type Lauren’s histology, and increases scirrhous-type stromal reactions, suggesting the SIRT3 functions as a tumor suppressor.


Other Topics in Gastroenterology

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