Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature
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1 Withdrawal of immunomodulators after co-treatment does not reduce trough level of infliximab in patients with Crohn's disease Clinical Gastroenterology and Hepatology , September 19, 2014    Clinical Article

2 Predictors of response to steroid therapy for eosinophilic esophagitis and treatment of steroid-refractory patients Clinical Gastroenterology and Hepatology , September 19, 2014    Clinical Article

3 Coffee, tea and decaffeinated coffee in relation to hepatocellular carcinoma in a European population: Multi-centre, prospective cohort study International Journal of Cancer, September 19, 2014    Clinical Article

4 Long-term use of antibiotics and proton pump inhibitors predict development of infections in patients with cirrhosis Clinical Gastroenterology and Hepatology , September 19, 2014    Clinical Article

5 Challenges of hepatitis C treatment in Native Americans in two North Dakota medical facilities Full Text Rural and Remote Health, September 19, 2014    Clinical Article

6 Provider-based research networks may improve early access to innovative colon cancer treatment for African Americans treated in the community Cancer, September 19, 2014    Clinical Article

7 Gastroprotective strategies in chronic NSAID users: A cost-effectiveness analysis comparing single-tablet formulations with individual components Value in Health, September 19, 2014    Clinical Article

8 Early use of low residue diet is superior to clear liquid diet after elective colorectal surgery: A randomized controlled trial Annals of Surgery, September 19, 2014    Clinical Article

9 Hepatitis B viral load affects prognosis of hepatocellular carcinoma Full Text World Journal of Gastroenterology, September 19, 2014    Clinical Article

10 A phase II study of catumaxomab administered intra- and postoperatively as part of a multimodal approach in primarily resectable gastric cancer Gastric Cancer, September 19, 2014    Clinical Article

11 Amiodarone use and risk of acute pancreatitis: a population-based case-control study Heart Rhythm, September 19, 2014    Clinical Article

12 Diagnosis and treatment of severely malnourished children with diarrhoea Journal of Paediatrics and Child Health, September 19, 2014    Evidence Based Medicine    Review Article

13 Re-thinking cancer immunotherapy: Using advanced cancer genetics in immune mediated eradication of gastrointestinal cancers Hepatology, September 19, 2014    Clinical Article

14 Significant variations in elastometry measurements made within short-term in patients with chronic liver diseases Clinical Gastroenterology and Hepatology , September 19, 2014    Clinical Article

15 Performance of new thresholds of the Glasgow Blatchford Score in managing patients with upper gastrointestinal bleeding Clinical Gastroenterology and Hepatology , September 19, 2014    Clinical Article

16 Botulinum toxin injection for hypercontractile or spastic esophageal motility disorders: may high-resolution manometry help to select cases? Diseases of the Esophagus, September 19, 2014    Review Article

17 Extraintestinal manifestations of Helicobacter pylori: A concise review Full Text World Journal of Gastroenterology, September 19, 2014    Review Article

18 Risk of drug-induced liver injury from tumor necrosis factor antagonists Clinical Gastroenterology and Hepatology , September 19, 2014    Clinical Article

19 Adjuvant chemotherapy for patients with primary hepatocellular carcinoma: A meta-analysis International Journal of Cancer, September 19, 2014    Evidence Based Medicine

20 Metformin does not reduce markers of cell proliferation in esophageal tissues of patients with Barrett's esophagus Clinical Gastroenterology and Hepatology , September 19, 2014    Clinical Article

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Highlights in Gastroenterology

KIT mutations associated with poor prognosis in GISTs

Based on a meta-analysis (18 studies; n=1487) reported in the World Journal of Surgical Oncology, KIT mutations in patients with gastrointestinal stromal tumors (GISTs) are associated with larger tumors (> 5 cm), higher mitotic activity (> 5), more frequent recurrences (OR = 2.06), more frequent metastases (OR = 2.77), and worse 3-year overall survival (OR = 0.47) compared to patients with PDGFRA mutations or wild-type.

Calcium reduces CRC risk

As reported in the International Journal of Cancer, there is an 8% reduction in CRC risk with each 300 mg/d increase in calcium intake based on 15 studies involving 12305 patients who took 250-1900 mg of calcium/day over a 3.3-16 year follow-up period. The beneficial effect extended beyond 1000 mg/d.

SIRT3 expression improves prognosis in gastric cancer

As reported in the World Journal of Surgery, SIRT3 expression improves the prognosis in patients with gastric cancer (n=221). Specifically, the 5-year OS was 51.2% and 39.1% in patients who do and do not express SIRT3, respectively. The 5-year DFS was 49.6% and 38.0% in patients who do and do not express SIRT3, respectively. Patients who do not express SIRT3 are characterized by increased poor cellular differentiation, increased diffuse-type Lauren’s histology, and increases scirrhous-type stromal reactions, suggesting the SIRT3 functions as a tumor suppressor.


Other Topics in Gastroenterology

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