The Latest Journal Articles in Gastroenterology

1Cognitive-behavioural therapy has no effect on disease activity but improves quality of life in subgroups of patients with inflammatory bowel disease: a pilot randomised controlled trialBMC Gastroenterology, May 06, 2015  Full Text  Clinical Article
2Use of acid-suppressive therapy before anti-reflux surgery in 2922 patients: a nationwide register-based study in DenmarkAlimentary Pharmacology and Therapeutics, May 06, 2015  Clinical Article
3Prediction of adherence to a gluten-free diet using protection motivation theory among adults with coeliac diseaseJournal of Human Nutrition and Dietetics, May 06, 2015  Review Article
4Coeliac disease and asthma association in children: the role of antibiotic consumptionEuropean Respiratory Journal , May 06, 2015  Clinical Article
5High hepatic and extrahepatic mortality and low treatment uptake in HCV-coinfected persons in the Swiss HIV cohort study between 2001 and 2013Journal of Hepatology, May 06, 2015  Clinical Article
6Efficacy and safety of pegylated interferon base treatment in patients with chronic hepatitis C on dialysisEuropean Journal of Internal Medicine , May 06, 2015  Review Article
7Next-generation sequencing panels for the diagnosis of colorectal cancer and polyposis syndromes: a cost-effectiveness analysis Journal of Clinical Oncology, May 06, 2015  Clinical Article
8Polybrominated diphenyl ethers and thyroid cancer risk in the prostate, colorectal, lung, and ovarian cancer screening trial cohortAmerican Journal of Epidemiology, May 06, 2015  Clinical Article
9Deep sequencing and phylogenetic analysis of variants resistant to interferon-based protease inhibitor therapy in chronic hepatitis induced by genotype 1b hepatitis C virusJournal of Virology, May 06, 2015  Clinical Article
10Pediatric inflammatory bowel disease: Imaging issues with targeted solutionsAbdominal Imaging , May 06, 2015  Clinical Article
1Nearly half a million Americans suffer from C. difficile infections in single yearCDC, May 06, 2015
2"Made in Michigan" times three: First clinical trials begin for drug developed at U-M and licensed to a U-M spinoff based on campusUniversity of Michigan Health System, May 05, 2015
3Biosimilar drug for infliximab launched in EuropeThe Rheumatologist, May 04, 2015
4Cryptosporidiosis surveillance - United States, 2011-2012Morbidity and Mortality Weekly Report, May 04, 2015
5Giardiasis surveillance - United States, 2011-2012Morbidity and Mortality Weekly Report, May 04, 2015
65-year survivors of esophageal cancer still face low but constant risksAmerican Association for Thoracic Surgery (AATS) Press Releases, May 04, 2015
7Leading Irish microbiome research institute partners with San-Francisco based Second GenomeScience Foundation Ireland News, May 04, 2015
8Pancreatic cancer risk linked to weak sunlightUC San Diego Health System, May 04, 2015
9Study shows promising results for curing hard-to-treat hepatitis C in patients awaiting or completing liver transplantUniversity of Texas Health Science Center at San Antonio News, May 04, 2015
10Patients with gastrointestinal tumors at higher risk of other cancersUC San Diego Health System, May 04, 2015

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Decreased PTPN12 expression associated with poor prognosis in HCC

As reported in PLoS ONE, the expression of PTPN12 was decreased in hepatocellular carcinoma tissue samples compared with adjacent normal tissues. Furthermore, decreased PTPN12 expression was associated with tumor recurrence, decreased cancer-specific survival, and decreased recurrence-free survival.

Risk factors for CHC-related death identified

As reported in the World Journal of Gastroenterology, the following risk factors for chronic hepatitis C (CHC)-related deaths have been identified (n=8250 CHC patients; n=144 CHC-related deaths): α-IFN therapy (AOR=0.53); liver cirrhosis (AOR=2.89); hepatocellular carcinoma versus CHC (AOR=8.82); hypertension (AOR=1.76); alcohol consumption (AOR=1.73); and HBsAg positivity (AOR=22.28).

Risk factors for intra-abdominal abscesses in Crohn’s disease

As reported in Digestion, uncontrolled CRP at week 14 of therapy with infliximab (OR=1.36) and early loss of response to infliximab (OR=5.36) are independent risk factors for intra-abdominal abscesses in patients with Crohn’s disease.

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