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The soluble form of the receptor of advanced glycation endproducts increases after bariatric surgery in morbid obesity
International Journal of Obesity, 07/18/2012
Brix JM et al. – Patients with morbid obesity (MO) have significantly lower soluble form of receptor of Advanced Glycation Endproducts (sRAGE) levels compared with non–obese CO, but sRAGE levels increase significantly after weight loss induced by bariatric surgery. As high sRAGE levels inhibit the activation of inflammatory pathways, the results might help understand the beneficial effects of bariatric surgery regarding cardiovascular (CV) morbidity and mortality.
