Bin1 Attenuation Suppresses Experimental Colitis by Enforcing Intestinal Barrier Function

Digestive Diseases and Sciences, 04/24/2012

Bin1 is a genetic modifier of experimental colitis that controls the paracellular pathway of transcellular ion transport regulated by cellular tight junctions. The findings offer a preclinical validation of Bin1 as a novel therapeutic target for inflammatory bowel disease (IBD) treatment.

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