High frequency of overlap between functional dyspepsia and overactive bladder

Neurogastroenterology & Motility, 05/25/2012

Overactive bladder syndrome is common among functional dyspepsia (FD) patients, even if they do not have irritable bowel syndrome (IBS). To improve FD patients’ quality of life, it will be important to provide management for Overactive bladder syndrome (OAB).


  • A web surveys containing questions about OAB, FD, IBS, and demographics were completed by 5494 public individuals (2302 men and 3192 women) who have no history of severe illness.
  • The prevalence and overlap of OAB, FD, and IBS were examined.


  • Among participants with FD, 20.5% could also be diagnosed with OAB (odds ratio [OR]: 2.85; 95% confidence interval [CI]: 2.21–3.67).
  • Although concomitant FD and IBS were more strongly associated with OAB (OR: 4.34; 95% CI: 2.81–6.73), OAB was also highly prevalent among participants with FD but without IBS (OR: 3.09; 95% CI: 2.29–4.18).
  • Among participants with FD, an overlapping OAB condition was more prevalent in those with both postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS) (OR: 3.75; 95% CI: 2.48–5.67) than in those with PDS or EPS alone.
  • Among participants with OAB, the severity of bladder symptoms was greater in participants with dyspeptic symptoms than without them.

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