Phase II and gene expression analysis trial of neoadjuvant capecitabine plus irinotecan followed by capecitabine-based chemoradiotherapy for locally advanced rectal cancer

Cancer Chemotherapy and Pharmacology, 05/24/2012

This neoadjuvant regimen was safe and demonstrated significant antitumor activity. High thymidine phosphorylase (TP) tumor gene expression was associated with obtaining pathological complete response (pCR).

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