Imatinib-induced liver cirrhosis in a patient with advanced gastrointestinal stroma tumor (GIST)

BMC Cancer, 05/24/2012

The report supports the notion that imatinib–induced hepatotoxicity may lead to acute liver damage with subsequent cirrhotic remodelling. Patients developing grade 3 or 4 hepatotoxicity during imatinib treatment should therefore be carefully evaluated for chronic liver disease.

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