The impact of colonoscopy for colorectal cancer screening

Surgical Endoscopy, 05/21/2012

The results of this investigation revealed a significant incidence of colonoscopic alterations in asymptomatic people submitted to colonoscopy for colorectal cancer screening.


  • A prospective study was undertaken on 153 consecutive asymptomatic people submitted to colonoscopy.
  • Sex, age, previous diseases, and familial cases of cancer, as well as tobacco and alcohol ingestion were assessed.
  • Patients with rectal macro– or microscopic bleeding and colorectal diseases were excluded.
  • Bowel cleansing, polyps, angioectasias, diverticular disease, inflammation, and neoplasm were also verified.
  • Polyps were classified according to their size, number, and location.


  • Colonoscopic alterations were detected in 99 individuals: polyps in 64.3 %, diverticular disease in 27.9 %, inflammatory mucosal alterations in 9.7 %, melanosis coli in 2.6 %, and angioectasias in 7.8 %.
  • There was an increasing incidence of polyps in individuals older than 50 years.
  • Multivariate logistic regression showed age and sex as predictive factors for polyps [odds ratio (OR) = 1.43; 1.19 < OR < 2.67].

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