The impact of colonoscopy for colorectal cancer screening
Surgical Endoscopy, 05/21/2012Alberti LR et al.
The results of this investigation revealed a significant incidence of colonoscopic alterations in asymptomatic people submitted to colonoscopy for colorectal cancer screening.
A prospective study was undertaken on 153 consecutive asymptomatic people submitted to colonoscopy.
Sex, age, previous diseases, and familial cases of cancer, as well as tobacco and alcohol ingestion were assessed.
Patients with rectal macro– or microscopic bleeding and colorectal diseases were excluded.
Bowel cleansing, polyps, angioectasias, diverticular disease, inflammation, and neoplasm were also verified.
Polyps were classified according to their size, number, and location.
Colonoscopic alterations were detected in 99 individuals: polyps in 64.3 %, diverticular disease in 27.9 %, inflammatory mucosal alterations in 9.7 %, melanosis coli in 2.6 %, and angioectasias in 7.8 %.
There was an increasing incidence of polyps in individuals older than 50 years.
Multivariate logistic regression showed age and sex as predictive factors for polyps [odds ratio (OR) = 1.43; 1.19 < OR < 2.67].
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