Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma

Hepatology, 05/07/2012

This leads to enhanced activator protein 1 (AP–1) activation and consequently to elevated expression of vascular endothelial growth factor (VEGF) and IL–8, which accelerate the growth of hepatocellular carcinomas (HCCs). Selenium supplementation could be considered for investigation as a strategy for chemoprevention or additional therapy of early HCC in patients with low selenium levels. et al. –

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