USP22 nuclear expression is significantly associated with progression and unfavorable clinical outcome in human esophageal squamous cell carcinoma

Journal of Cancer Research & Clinical Oncology, 03/29/2012

USP22 protein plays an essential role in esophageal squamous cell carcinoma (ESCC) progression and has clinical potentials not only as a promising biomarker to identify the subgroup of patients with more aggressive tumors and poor prognostic potential but also as an attractively therapeutic target for ESCC.

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