Is There any Benefit from Expanding the Criteria for the Resection of Hepatocellular Carcinoma in Cirrhotic Liver? Experience from a Developing Country

World Journal of Surgery, 03/28/2012

RF–assisted sequentional “coagulate–cut liver resection technique“ may be a viable alternative for management of patients with advanced HCC in cirrhotic liver with impaired function.

Methods

  • Forty patients with Child–Pugh A or B cirrhosis underwent liver resection from December 1, 2001 to December 31, 2008.
  • Of these, 20 patients (13 Child–Pugh A and 7 Child–Pugh B) with advanced stage HCC (stage B and C according to Barcelona–Clinic Liver Cancer Group) underwent major liver resection.
  • The two groups were comparable in terms of patient age, liver cirrhosis etiology, tumor number, and size.

Results

  • All resections were performed without the Pringle maneuver.
  • There was no significant difference found between the two groups regarding resection time, perioperative transfusion, postoperative complications, hospital stay, and day 7 values of hemoglobin and liver enzymes.
  • Likewise, there was no significant difference found in the overall survival between Child A and Child B patients who underwent major liver resection

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