Gastroenterology News & Articles

1 Symptom Overlap Between Postprandial Distress and Epigastric Pain Syndromes of the Rome III Dyspepsia Classification The American Journal of Gastroenterology, April 17, 2013
Vakil N et al. - The Rome III criteria for functional dyspepsia recognize two distinct subgroups: postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS). The aim of this exploratory analysis was to evaluate the Rome III criteria and the validity of the PDS/EPS subgrouping in primary care patients with upper gastrointestinal symptoms. PDS and EPS overlap in the majority of patients with functional dyspepsia. The value of dividing functional dyspepsia into the subgroups of ...

2 Burden of comorbidities among Japanese patients with atrial fibrillation: a case study of dyspepsia Clinical and Experimental Gastroenterology, May 21, 2013
Kinoshita Y et al. - The aim of this study was to investigate the link between atrial fibrillation (AF) and dyspepsia, as well as the contribution of dyspepsia to the overall burden of AF. Patients with AF in Japan experience a number of comorbidities, with dyspepsia being the most common noncardiovascular comorbidity. Given the prevalence and additional burden of this comorbidity across both humanistic and economic outcomes, the management of dyspepsia among patients with AF should be ...

3 Impact of sleep disorders in Japanese patients with functional dyspepsia (FD): nizatidine improves clinical symptoms, gastric emptying and sleep disorders in FD patients Journal of Gastroenterology and Hepatology, April 24, 2013
Yamawaki FS et al. - The association between functional dyspepsia (FD) and sleep disorders has yet to be studied in detail. The aim of this study is to evaluate the risk factors associated with sleep disorders and the clinical response to nizatidine therapy for sleep disorders in Rome III-based FD patients. Sleep disorders in FD patients correlated significantly with both clinical symptoms of dyspepsia and depression compared to healthy volunteers. Nizatidine significantly improved ...

4 A randomized controlled trial of brief psychoanalytic psychotherapy in patients with functional dyspepsia Asian Journal of Psychiatry, May 3, 2013
Faramarzi M et al. - Functional dyspepsia (FD) is a common cause of upper gastrointestinal symptoms and discomfort. The present study aimed to assess the effectiveness of brief core conflictual relationship theme (CCRT) psychoanalytic psychotherapy on changing gastrointestinal symptoms, alexithymia, and defense mechanisms in patients with FD. Brief psychodynamic therapy is a reliable method to improve gastrointestinal symptoms, mature defenses, and alexithymia scores in patients with ...

5 A Rome III survey of functional dyspepsia among the ethnic Malays in a primary care setting BMC Gastroenterology, May 15, 2013
Lee YY et al. - The study aimed to survey for FD in a primary care setting in a population known to have an extremely low prevalence of Helicobacter pylori (H. pylori) infection, with the hypothesis that in such a population, dyspepsia should have been relatively less common. FD was more common than one had expected among Malays attending primary care clinic in an area with low prevalence of H. pylori.

6 Clinical characteristics and effectiveness of lansoprazole in Japanese patients with gastroesophageal reflux disease and dyspepsia Journal of Gastroenterology, May 8, 2013
Kinoshita Y et al. - The aim of this study was to clarify the therapeutic effect of lansoprazole on dyspepsia in Japanese patients with gastroesophageal reflux disease (GERD). In this large-scale clinical study, lansoprazole effectively relieved dyspepsia in addition to reflux symptoms in patients with GERD.

7 Impact of Laparoscopic Sleeve Gastrectomy on Upper Gastrointestinal Symptoms Obesity Surgery, May 2, 2013
Carabotti M et al. – This study aims to evaluate laparoscopic sleeve gastrectomy (LSG)'s impact on the prevalence of upper GI symptoms and to assess the effects of time from surgery, weight loss, and proton pump inhibitor (PPI) therapy. After a median follow–up of 13 months, PDS–like dyspepsia, rather than GERD, was the main complaint, both poorly responding to PPI therapy. Methods The validated Rome III Criteria symptom questionnaire for upper GI symptoms, including quality of life ...

8 Functional dyspepsia: the economic impact to patients Alimentary Pharmacology and Therapeutics, June 14, 2013
Lacy BE et al. - The study aims to quantify functional dyspepsia (FD). patients' health care utilisation patterns and to estimate direct and indirect costs of FD to patients. Functional dyspepsia patients incur significant direct and indirect costs and work productivity is impaired by dyspeptic symptoms.

9 Improvement of quality of life and symptoms after gastric electrical stimulation in children with functional dyspepsia Neurogastroenterology & Motility, March 7, 2013
Lu PL et al. - The objective is to evaluate the effect of gastric electrical stimulation (GES) on symptoms and quality of life for pediatric patients with functional dyspepsia (FD). In the largest series to date of pediatric patients who have undergone GES for FD, the authors found significant improvements in upper gastrointestinal symptoms, quality of life, and perception of global health. Patients were less dependent on tube feeding or parenteral nutrition.

10 Gastric emptying and antral motility parameters in children with functional dyspepsia: association with symptom severity Journal of Gastroenterology and Hepatology, April 10, 2013
Devanarayana NM et al. - Functional dyspepsia (FD) is an important gastrointestinal problem with obscure aetiology. Abnormal gastric motility is suggested as a possible pathophysiological mechanism for symptoms. The main objective of this study was to assess gastric motility in Sri Lankan children with FD. Gastric emptying rate (GE) and antral motility parameters were significantly impaired in children with FD compared to controls. GE negatively correlated with severity of symptoms. This ...