Available now at MDLinx Gastroenterology: Ranked summaries of the most clinically-relevant GI literature refreshed every 24 hours, as well as MDLinx Gastroenterology exclusive content
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1 The effect of different dosing regimens of motesanib on the gallbladder: a randomized phase 1b study in patients with advanced solid tumors Full Text BMC Cancer, May 17, 2013 Clinical Article
2 Cruciferous vegetables consumption and gastric cancer risk: a meta-analysis of epidemiological studies Cancer Science, May 17, 2013 Evidence Based Medicine
3 Prevalence of obesity and extreme obesity in children aged 3–5 years Pediatric Obesity, May 17, 2013 Review Article
4 C-Reactive Protein, Lipid-soluble Micronutrients, and Survival in Colorectal Cancer Patients Cancer Epidemiology, Biomarkers & Prevention, May 17, 2013 Clinical Article
5 Multivisceral Resection in Colorectal Cancer: A Systematic Review Annals of Surgical Oncology, May 17, 2013 Evidence Based Medicine Review Article
6 The accuracy of multi-detector row computerized tomography in staging rectal cancer compared to endoscopic ultrasound Full Text Saudi Journal of Gastroenterology, May 17, 2013 Clinical Article
7 Prevalence and risk factors of extrapancreatic malignancies in a large cohort of patients with intraductal papillary mucinous neoplasm (IPMN) of the pancreas Annals of Oncology, May 17, 2013 Clinical Article
8 Chemotherapeutic and Targeted Strategies for Locally Advanced and Metastatic Esophageal Cancer Journal of Thoracic Oncology, May 17, 2013 Review Article
9 Celiac Disease and Autoimmunity: Review and Controversies Current Allergy and Asthma Reports, May 17, 2013 Review Article
10 Elevated liver enzymes in individuals with undiagnosed diabetes in the U.S. Journal of Diabetes and its Complications, May 17, 2013 Clinical Article
11 Clinical, MRI, and PET-CT Criteria Used by Surgeons to Determine Suitability for Pelvic Exenteration Surgery for Recurrent Rectal Cancers: A Delphi Study Diseases of the Colon and Rectum, May 17, 2013 Clinical Article
12 Do probiotics improve eradication response to Helicobacter pylori on standard triple or sequential therapy? Full Text Saudi Journal of Gastroenterology, May 17, 2013 Clinical Article
13 Long-term follow-up of children exposed intrauterine to maternal thiopurine therapy during pregnancy in females with inflammatory bowel disease Alimentary Pharmacology and Therapeutics, May 17, 2013 Clinical Article
14 Anti-reflux surgery for patients with esophageal atresia Diseases of the Esophagus, May 17, 2013 Review Article
15 Prognostic Value of the D-Dimer Test in Oesophageal Cancer During the Perioperative Period Journal of Surgical Oncology, May 17, 2013 Clinical Article
16 Laparoscopic Hellers myotomy versus pneumatic dilation in the treatment of idiopathic achalasia: a meta-analysis of randomized, controlled trials Gastrointestinal Endoscopy, May 17, 2013 Evidence Based Medicine Clinical Article
17 Predictors of the change in bilirubin levels over twelve weeks of treatment with atazanavir Full Text AIDS Research and Therapy, May 17, 2013 Clinical Article
18 Sphincter preservation in anal cancer: A brief review Full Text Saudi Journal of Gastroenterology, May 17, 2013 Review Article
19 Mucosal healing with oral tacrolimus is associated with favorable medium- and long-term prognosis in steroid-refractory/dependent ulcerative colitis patients Journal of Crohn's and Colitis, May 17, 2013 Review Article
20 Feeding difficulties in children with esophageal atresia: treatment by a multidisciplinary team Diseases of the Esophagus, May 17, 2013 Review Article
As published in the NEJM, researchers in the COLONPREV study (Spain) have reported that fecal immunochemical testing (FIT) is as effective as colonoscopy in the detection of colorectal cancer (CRC). The study population was 50-69 years of age and comprised of 26,703 subjects who underwent a one-time colonoscopy and 26,599 subjects who underwent FIT every 2 years. The primary outcome measure was CRC deaths at 10 years. Participation in screening was greater in the FIT group than the colonoscopy group (34.2% vs. 24.6%). Detection of CRC was similar between the two groups (0.1%). Advanced and non-advanced adenomas were detected more frequently in the colonoscopy group than the FIT group (1.9% vs. 0.9% [OR=2.3] and 4.2% vs. 0.4% [OR=9.8], respectively).
Read the article summaryBased on a meta-analysis involving 30 observational studies and 202,965 patients, proton pump inhibitor therapy has been shown to significantly increase the risk of infection with Clostridium difficile (OR = 2.15).
Read the article summaryIn a single institution study involving 424 patients with DM and CRC, those patients treated with metformin had a 30% improvement in OS compared with patients not treated with metformin. Specifically, the metformin-treated patients had a mean survival of 76.9 months compared to 56.9 months.
Read the article summary1 Systematic review: pentoxifylline for the treatment of severe alcoholic hepatitis Alimentary Pharmacology and Therapeutics, April 3, 2013 Review Article
2 Risk of Colorectal Cancer After Colonoscopy Compared With Flexible Sigmoidoscopy or No Lower Endoscopy Among Older Patients in the United States, 1998-2005 Mayo Clinic Proceedings, April 11, 2013
3 Probiotics in the management of irritable bowel syndrome and inflammatory bowel disease Current Opinion in Gastroenterology, February 20, 2013
4 Meta-analysis: peri-operative anti-TNF treatment and post-operative complications in patients with inflammatory bowel disease Alimentary Pharmacology and Therapeutics, April 18, 2013
5 Low allopurinol doses are sufficient to optimize azathioprine therapy in inflammatory bowel disease patients with inadequate thiopurine metabolite concentrations European Journal of Clinical Pharmacology, April 25, 2013
6 Statins in Nonalcoholic Fatty Liver Disease and Steatohepatitis: Updated Review Current Atherosclerosis Reports, January 21, 2013 Review Article
7 Ischemic Colitis with Type I Interferons Used in the Treatment of Hepatitis C and Multiple Sclerosis: An Evaluation from the Food and Drug Administration Adverse Event Reporting System and Review of the Literature Annals of Pharmacotherapy, April 3, 2013 Review Article
8 Association Between Sex Hormones and Colorectal Cancer Risk in Men and Women Clinical Gastroenterology and Hepatology , April 5, 2013
9 Comparison of the Diagnostic Accuracy of Five Different Stool Antigen Tests for the Diagnosis of Helicobacter pylori Infection Helicobacter, April 5, 2013
10 Five-year follow-up of 263 cases of functional bowel disorder World Journal of Gastroenterology, March 29, 2013 Free full text
11 Relationship of Non-alcoholic Fatty Liver Disease With Cholecystectomy in the US Population The American Journal of Gastroenterology, April 11, 2013
12 Meta-analysis: colonoscopic post-polypectomy bleeding in patients on continued clopidogrel therapy Alimentary Pharmacology and Therapeutics, April 12, 2013 Review Article
13 Clinical utility of newly developed immunoassays for serum concentrations of adalimumab and anti-adalimumab antibodies in patients with Crohns disease Journal of Gastroenterology, April 15, 2013
14 Meta-analysis: pegylated interferon -2a achieves higher early virological responses than -2b in chronic hepatitis C Alimentary Pharmacology and Therapeutics, April 16, 2013
15 Psychotherapy for inflammatory bowel disease: A review and update Journal of Crohn's and Colitis, March 25, 2013 Review Article
16 Association between adherence to concomitant proton pump inhibitor therapy in current NSAID users and upper gastrointestinal complications European Journal of Gastroenterology & Hepatology, April 18, 2013
17 Once-daily budesonide MMX in active, mild-to-moderate ulcerative colitis: results from the randomised CORE II study Gut, March 6, 2013
18 Characterization of virologic escape in hepatitis C virus genotype 1b patients treated with the direct-acting antivirals daclatasvir and asunaprevir Journal of Hepatology, April 8, 2013
19 Statin therapy improves response to interferon alfa and ribavirin in chronic hepatitis C: a systematic review and meta-analysis Antiviral Research , April 23, 2013 Evidence Based Medicine Review Article
20 Preoperative use of anti-TNF therapy and postoperative complications in inflammatory bowel diseases: A meta-analysis Journal of Crohn's and Colitis, March 27, 2013
Indexed Journals in Gastroenterology: Gastroenterology, American Journal of Gastroenterology, Gut more
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