We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Impact of immunosuppressive therapy on hepatitis B vaccination in inflammatory bowel diseasesEuropean Journal of Gastroenterology & Hepatology, July 07, 2015  Clinical Article
2Clinical management of patients with parenteral nutrition–dependent short bowel syndrome during teduglutide therapyJournal of Parenteral and Enteral Nutrition, July 07, 2015  Clinical Article
3A phase II study of biweekly S-1 and paclitaxel (SPA) as first-line chemotherapy in patients with metastatic or advanced gastric cancerCancer Chemotherapy and Pharmacology, July 07, 2015  Clinical Article
4Prevalence of coeliac disease in idiopathic hypoparathyroidism and effect of gluten free diet on calcaemic controlClinical Endocrinology, July 07, 2015  Clinical Article
5Liver fibrosis by transient elastography and virologic outcomes after introduction of tenofovir in lamivudine-experienced adults with HIV and hepatitis B virus coinfection in GhanaClinical Infectious Diseases, July 07, 2015  Clinical Article
6Efficacy and safety of diosmectite in acute childhood diarrhoea: A meta-analysisArchives of Diseases in Childhood, July 07, 2015  Evidence Based Medicine
7Safety of gadoxetate disodium: results from six clinical phase IV studies in 8194 patientsActa Radiologica, July 07, 2015  Clinical Article
8Serum hyaluronic acid in chronic viral hepatitis B and C: A biomarker for assessing liver fibrosis in chronic hemodialysis patientsInternational Urology and Nephrology, July 07, 2015  Clinical Article
9Risk factors for 30-day readmission following colorectal surgery: A systematic reviewJournal of Surgical Research, July 07, 2015  Evidence Based Medicine  Review Article
10Somatostatin analogues improve health-related quality of life in polycystic liver disease: a pooled analysis of two randomised, placebo-controlled trialsAlimentary Pharmacology and Therapeutics, July 07, 2015  Clinical Article

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We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Colon cancer: Taking a step back to move forwardWeizmann Institute of Science News, July 07, 2015
2The importance of placebos to medical careBeth Israel Deaconess Medical Center, July 06, 2015
3Cause of acute liver failure in young children discoveredTechnische Universität München, July 06, 2015
4Singapore team's discovery of new genomic aberrations of gastric cancer could pave the way for precision medicineAgency for Science, Technology and Research (A*STAR) News, July 06, 2015
5Abdominal blood clots may indicate undiagnosed cancerAarhus University Health News, July 06, 2015
6World GI 2015: Studies confirm regorafenib benefit in pre-treated metastatic colorectal cancerEuropean Society for Medical Oncology News, July 06, 2015
7McMaster researchers test fecal transplantation to treat ulcerative colitisMcMaster University Faculty of Health Sciences News, July 06, 2015
8Discovery promises new treatments to thwart colon cancerSt. Jude Children's Research Hospital News, July 06, 2015
9World GI 2015: Second-line cetuximab active beyond progression in quadruple wild-type patients with metastatic colorectal cancerEuropean Society for Medical Oncology News, July 06, 2015
10Anxiety increases the risk of gastrointestinal infection and long-term complicationsFlanders Institute for Biotechnology (VIB) News, July 03, 2015

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SCCA-IgM predicts survival in HCC patients

As reported in the Journal of Gastroenterology & Hepatology, SCCA-IgM levels are elevated in patients with hepatocellular carcinoma (HCC) compared to patients with cirrhosis and healthy controls. Not only does the SCCA-IgM level predict overall and progression-free survival in HCC patients, but the sensitivity of SCCA-IgM in patients with HCC was 2-fold greater than AFP. A decline in SCCA-IgM levels was shown to be associated with response to treatment.

Elevated ?-GT predicts HCC in hepatitis C patients with sustained response

As reported in the Journal of Hepatology, an elevated baseline ɣ-GT level is the strongest predictor of developing HCC in non-cirrhotic patients with hepatitis C and a sustained virologic response (HR = 6.44), followed by age (HR = 3.68).

Calcium reduces CRC risk

As reported in the International Journal of Cancer, there is an 8% reduction in CRC risk with each 300 mg/d increase in calcium intake based on 15 studies involving 12305 patients who took 250-1900 mg of calcium/day over a 3.3-16 year follow-up period. The beneficial effect extended beyond 1000 mg/d.

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Clinical Pearls

Clinical Pearl from Smartest DocAge is not an independent prognostic factor for gastric cancer patients undergoing curative resection.

Clinical Pearl from Smartest DocMetabolic syndrome is a significant risk factor for occurrence of advanced adenoma after a negative colonoscopy.

Clinical Pearl from Smartest DocHCV-related cryoglobulinemia commonly causes peripheral neuropathy.

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