Gastroenterology News Articles

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The latest in Gastroenterology: Ranked summaries of the most clinically-relevant GI literature updated every 24 hours, as well as exclusive content for gastroenterologists. Our team of dedicated physician medical editors sort, rank and summarize articles in over 2,000 medical journals to bring you the key developments in Gastroenterology. In addition to general news, you'll find subspecialty coverage of the biliary system and pancreas, colorectal cancer and polyps, hepatology and liver disease, GI bleeding, GI infectious diseases, gastrointestinal endoscopy, obesity, parenteral and enteral nutrition, diagnostic imaging, and more.

Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Exclusive enteral nutritional therapy can relieve inflammatory bowel stricture in Crohn’s disease Journal of Clinical Gastroenterology, September 17, 2014    Clinical Article

2 Medication use and medical comorbidity in patients with chronic hepatitis C from a US commercial claims database: high utilization of drugs with interaction potential European Journal of Gastroenterology & Hepatology, September 17, 2014    Clinical Article

3 Inflammatory bowel disease is associated with an increased risk of hospitalization for heart failure Circulation: Heart Failure, September 17, 2014    Clinical Article

4 The prevalence of dysphagia among adults in the United States Otolaryngology - Head and Neck Surgery, September 17, 2014    Clinical Article

5 Differences in surgical outcomes between hepatitis B- and hepatitis C - related hepatocellular carcinoma: A retrospective analysis of a single North American Center Annals of Surgery, September 17, 2014    Clinical Article

6 Correlation between oropharyngeal pH-monitoring and esophageal pH-impedance monitoring in patients with suspected GERD-related extra-esophageal symptoms Neurogastroenterology & Motility, September 17, 2014    Clinical Article

7 Failure of evidence-based cancer care in the United States: the association between rectal cancer treatment, cancer center volume, and geography Annals of Surgery, September 17, 2014    Clinical Article

8 Perception of lactose intolerance in irritable bowel syndrome patients European Journal of Gastroenterology & Hepatology, September 17, 2014    Clinical Article

9 Increasing biopsy number and sampling from gastric body improve the sensitivity of rapid urease test in patients with peptic ulcer bleeding Digestive Diseases and Sciences, September 17, 2014    Clinical Article

10 Effectiveness of nonsteroidal anti-inflammatory drugs in prevention of post-ERCP pancreatitis: A meta-analysis Full Text World Journal of Gastroenterology, September 17, 2014    Evidence Based Medicine    Clinical Article

11 Outcomes at one-year post anastomosis from a national cohort of infants with esophageal atresia PLOS ONE, September 17, 2014    Clinical Article

12 The association of type and number of chronic diseases with breast, cervical, and colorectal cancer screening Full Text Journal of the American Board of Family Medicine, September 17, 2014    Clinical Article

13 Prospective validation of Baveno V definitions and criteria for failure to control bleeding in portal hypertension Hepatology, September 17, 2014    Clinical Article

14 Orange juice intake reduces patient discomfort and is effective for bowel cleansing with polyethylene glycol during bowel preparation Diseases of the Colon and Rectum, September 17, 2014    Clinical Article

15 Sofosbuvir plus ribavirin in Japanese patients with chronic genotype 2 HCV infection: An open-label, phase 3 trial Journal of Viral Hepatitis, September 17, 2014    Clinical Article

16 Down-regulation of argininosuccinate synthetase is associated with cisplatin resistance in hepatocellular carcinoma cell lines: Implications for PEGylated arginine deiminase combination therapy Full Text BMC Cancer, September 17, 2014    Clinical Article

17 Evaluation of the World Health Organization 2010 grading system in surgical outcome and prognosis of pancreatic neuroendocrine tumors Pancreas, September 17, 2014    Review Article

18 Helicobacter pylori infection in Mongolian gerbils does not initiate hematological diseases Full Text World Journal of Gastroenterology, September 17, 2014    Clinical Article

19 Clinical implication of immunoglobulin G levels in the management of patients with Helicobacter pylori Infection Full Text Journal of the American Board of Family Medicine, September 17, 2014    Clinical Article

20 Early viral kinetics with telbivudine, tenofovir or combination of both in immunotolerant patients with hepatitis B e antigen-positive chronic hepatitis B Full Text Infectious Diseases and Therapy, September 17, 2014    Clinical Article

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Highlights in Gastroenterology

Calcium reduces CRC risk

As reported in the International Journal of Cancer, there is an 8% reduction in CRC risk with each 300 mg/d increase in calcium intake based on 15 studies involving 12305 patients who took 250-1900 mg of calcium/day over a 3.3-16 year follow-up period. The beneficial effect extended beyond 1000 mg/d.

KIT mutations associated with poor prognosis in GISTs

Based on a meta-analysis (18 studies; n=1487) reported in the World Journal of Surgical Oncology, KIT mutations in patients with gastrointestinal stromal tumors (GISTs) are associated with larger tumors (> 5 cm), higher mitotic activity (> 5), more frequent recurrences (OR = 2.06), more frequent metastases (OR = 2.77), and worse 3-year overall survival (OR = 0.47) compared to patients with PDGFRA mutations or wild-type.

Risk factors for intra-abdominal abscesses in Crohn’s disease

As reported in Digestion, uncontrolled CRP at week 14 of therapy with infliximab (OR=1.36) and early loss of response to infliximab (OR=5.36) are independent risk factors for intra-abdominal abscesses in patients with Crohn’s disease.

Other Topics in Gastroenterology

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