Family Med Medical News about Arthritis, Rheumatoid Fatigue Osteoarthritis

Become a Member Today!
Register

Most Viewed Abstracts

1. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease

2. Omega-3 fatty acids for bipolar disorder

3. Is folic acid good for everyone

4. ACS Releases Guidelines for HPV Vaccination

5. Vitamin D - A review Free full text

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

A comparison of fatigue correlates in rheumatoid arthritis and osteoarthritis: Disparity in associations with disability, anxiety and sleep disturbance
Rheumatology, 12/14/09

Stebbings S et al. – The goal of this study was to investigate correlates of fatigue among individuals with RA and OA, including mood, sleep, disease activity and radiographic damage. Fatigue is common and severe in both RA and OA. In RA, fatigue had no significant association with pain, disease activity, disability or erosions, but was associated with depression and anxiety. The disparity in correlates indicates that generalizing the experience of fatigue between OA and RA is not appropriate. Fatigue is an important domain in the assessment of disease impact.

Methods

Fatigue assessed using Multidimensional Assessment of Fatigue-Global Fatigue Index (MAF-GFI) in 103 patients with RA and 103 with OA
Sleep disturbance and pain assessed using visual analogue scale anxiety and depression using Hospital Anxiety and Depression scale and disability using HAQ
In RA cohort, disease activity score-28 joint count (DAS-28) and the Van der Heijde modified Sharp score were calculated, and in OA cohort, the Kellgren–Lawrence score and WOMAC score calculated

Results

MAF-GFI scores higher in OA cohort
This was not significant after controlling for disability
OA participants reported greater pain, disability, depression and sleeplessness than those with RA
strongest correlates of fatigue in the RA cohort were depression and anxiety
No significant association with pain , DAS-28 , HAQ or Sharp score
In OA, correlates of fatigue were older age (P = 0.02), sleep disturbance , depression , disability and lower CRP

<< Previous
Comparative, double-blind, controlled study of intra-articular...

Next >>
A qualitative study of lifestyle counselling in general practice...