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See Latest ArticlesUpdate in treatment options for psoriatic arthritis
Expert Review of Clinical Immunology, 11/23/09
De Vlam K et al. – Psoriatic arthritis is a chronic inflammatory joint disease in patients with psoriasis and has a varying disease course. Treatment options for peripheral disease, enthesitis and dactylitis include nonsteroidal anti–inflammatory drugs (NSAIDs), disease–modifying antirheumatic drugs (DMARDs), local steroids and TNF–blocking agents. Axial disease is treated with NSAIDS and TNF blockade. Major clinical response is seen in approximately 30% of patients with methotrexate or leflunomide but no structural effect has yet been documented. Anti–TNF treatment has the best number–needed– to–treat/number–needed–to harm ratio of all DMARDs in psoriatic arthritis and is able to induce clinical remission in at least 30% of patients. TNF–blocking agents have also been demonstrated to slow down or halt radiographic progression.
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