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Effect of Season of Inoculation on Immune Response to Rubella Vaccine in Children
Journal of Tropical Pediatrics, 11/05/09
Linder N et al. – This preliminary study shows a strong correlation between the immune response to rubella vaccine and the season of vaccination. Immunogenicity may be improved by inoculating children during seasons of less sunlight or by reducing the children's exposure to sunlight following inoculation. This practice is especially important in areas with extreme seasonal variability in solar radiation and tropical areas. Further studies are needed to corroborate and expand these findings.
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