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Altered Effect of Dopamine Transporter 3UTR VNTR Genotype on Prefrontal and Striatal Function in Schizophrenia
Archives of General Psychiatry, 11/06/09
Prata DP et al. – Insular, cingulate, and striatal function during an executive task is normally modulated by variation in the dopamine transporter gene. Its effect on activation in the dorsolateral prefrontal cortex and ventral striatum is altered in patients with schizophrenia. This may reflect altered dopamine function in these regions in schizophrenia.
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