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See Latest ArticlesPsychopharmacology and adverse effects of antipsychotic long-acting injections: a review
British Journal of Psychiatry, 11/09/09
Taylor D et al. – Dosing of LAIs is complicated by delayed release of drug, changes in plasma levels without change in dose, and by the lack of data establishing clear dose requirements. All LAIs offer the prospect of assured adherence (although patients may still default on treatment) but their use is complicated by adverse effects, complex pharmacokinetics and confusion over dose–response relationships.
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