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See Latest ArticlesThe Molecular Mechanisms Regulating Germ Cell Development and Potential
Journal of Andrology, 11/02/09
Matsui Y – The authors found that the precursor cells of PGCs require E–cadherin–mediated cell–cell interaction and the functions of transcription factor Oct3/4 to be specified to PGCs. Once they have undergone specification and differentiation, PGCs normally give rise to gametes, but they maintain the potential to be converted into pluripotential stem cells upon activation of particular signaling pathways.
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