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See Latest ArticlesDeregulation of cell-death pathways as the cornerstone of skin diseases
Clinical and Experimental Dermatology, 11/03/09
Zutterman N et al. – Deregulation of cell–death pathways plays a key role in the pathogenesis of various skin diseases. The different types of cell death are mainly defined by morphological criteria, and include apoptosis, autophagic cell death, and necrosis. The process of apoptosis is well characterized at the molecular level and involves the activation of two main pathways, the intrinsic and extrinsic pathways, converging into the execution of apoptosis by intracellular cysteine proteases, called caspases.
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