Family Med Medical News about Gastrointestinal Tract Hemorrhage Platelet Aggregation Inhibitors

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A comparison of aspirin and clopidogrel with or without proton pump inhibitors for the secondary prevention of cardiovascular events in patients at high risk for gastrointestinal bleeding
Clinical Therapeutics, 10/29/09

Hsiao F–Y et al. – In this analysis in patients at high GI risk who were receiving antiplatelet therapy for the secondary prevention of cardiovascular events, aspirin plus a PPI was associated with a reduced risk of recurrent hospitalization for major GI complications. This was not the case for clopidogrel plus a PPI.

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Dual antiplatelet therapy in coronary artery disease: A case-based approach
Cleveland Clinic Journal of Medicine, 11/04/09 Relevance Score: 77%

Insights into the interpretation of light transmission aggregometry for evaluation of platelet aggregation inhibition by clopidogrel
Thrombosis Research, 10/20/09 Relevance Score: 70%

Acidic-store depletion is required for human platelet aggregation
Blood Coagulation & Fibrinolysis, 10/05/09 Relevance Score: 69%

Platelet Aggregation in Intracranial Stents May Mimic In-Stent Restenosis
American Journal of Neuroradiology, 11/02/09 Relevance Score: 68%

Platelet Cyclic Guanosine Monophosphate as a Biomarker of Phosphodiesterase Type 5 Inhibitor Efficacy in the Treatment of Erectile Dysfunction: A Randomized Placebo-Controlled Study
European Urology, 11/05/09 Relevance Score: 67%