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See Latest ArticlesIncomplete Penetrance of the Predisposition to Medulloblastoma Associated With Germ-Line Sufu Mutations
Journal of Medical Genetics, 10/29/09
Brugieres L et al. – The report highlights three features of SUFU–related tumors. These are mainly medulloblastomas with extensive nodularity or classic desmoplastic/nodular medulloblastomas. These tumors mostly appear during the first three years of life. The penetrance of the mutation may be low.
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