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See Latest ArticlesThe transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
Proceedings of the National Academy of Sciences of the United States of America, 10/22/09
Jenner RG et al. – The data show that the choice between Th1 and Th2 lineage commitment is the result of the opposing action of T–bet and GATA–3 at a shared set of target genes and may provide a general paradigm for the interaction of lineage–specifying transcription factors.
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