Family Med Medical News about Fat Emulsions, Intravenous

Become a Member Today!
Register

Most Viewed Abstracts

1. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease

2. Omega-3 fatty acids for bipolar disorder

3. Is folic acid good for everyone

4. ACS Releases Guidelines for HPV Vaccination

5. Vitamin D - A review Free full text

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Formulation, Stability, and Administration of Parenteral Nutrition With New Lipid Emulsions
Nutrition in Clinical Practice, 10/29/09

Hardy G et al. – Intravenous lipid emulsions (IVLE) are an important source of energy and essential fatty acids and their incorporation into pediatric and adult parenteral nutrition (PN) regimens has revolutionized nutrition therapy. However, their clinical use has not been without risk, and will continue to remain so because of the intravenous route of administration. Pharmaceutical and microbiological concerns are centered around the methods of compounding all–in–one (AIO) admixtures, but these can be largely minimized with today’s technologies and advanced understanding of aseptic principles. Modern lipid products, based on olive, coconut, and/or fish oils, have demonstrable formulation and clinical benefits over traditional soybean and safflower IVLE and, when combined in the new multi–chamber bags, can also offer improvements in stability and safety. This review outlines the rationale for different lipid formulations in PN admixtures, reviews the factors influencing stability and efficacy of lipid–based AIO regimens and evaluates some technologies for minimizing peroxidation and maximizing stability of AIO admixtures.

<< Previous
Enteral Nutrition in Nursing Home Residents: A 5-Year (2001-2005)...

Next >>
Hyperglycemic Events in Non-Intensive Care Unit Patients...