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Tonstad S et al. – Assay of CRP levels may be useful in monitoring disease progression and determining risk of future cardiovascular complications. However, as this marker is also an indicator of acute inflammation and challenges to the immune system, some caution must be exercised in interpreting the available data on CRP levels in patients with different chronic comorbidities.

Exclusive Author Commentary
Serena Tonstad, 10/12/09

CRP levels are expected to decrease with smoking cessation, however, the relation between stopping smoking and CRP is still not firmly established. Other diseases confound this relationship. Even in smokers without confounding comorbidities, it may take 1 year or more before levels of CRP return to normal after cessation.


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