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See Latest ArticlesThe first Pandemic of the 21st Century: A Review of the 2009 Pandemic Variant Influenza A (H1N1) Virus
Postgraduate Medicine, 10/02/09
Scalera NM et al. – Swine influenza was first described in the 1918 pandemic and made a resurgence in April 2009 in the form of a triple–reassortant influenza A virus, which is composed of a combination of human, swine, and Eurasian avian strains. As evidenced with previous influenza pandemics, young adults and children aged < 24 years are the population most affected. Definitive diagnosis has largely been limited by the inability of conventional influenza testing to distinguish among influenza A subtypes; however, the surge in pandemic cases clearly emerged at the end of the annual influenza season in the northern hemisphere. The pandemic variant influenza A (H1N1) strain is typically susceptible to oseltamivir and resistant to adamantanes, unlike the 2008 to 2009 seasonal influenza A (H1N1). However, 2 cases of oseltamivir–resistant pandemic–variant influenza A (H1N1) were reported in late August 2009.
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