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The Replacement of Cytogenetic Analysis by Direct Chorionic Villi Sampling Preparation with Quantitative Fluorescence PCR
Gynecologic and Obstetric Investigation, 09/24/09
Velissariou V et al. – QF–PCR can replace chromosomal analysis of CV–DIR in most cases during routine prenatal diagnosis, requiring smaller CV samples and being more labor effective. Coupled with LTC, it is a robust diagnostic approach with high predictive value for the most frequent fetal trisomies.
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