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See Latest ArticlesHighly active antiretroviral therapy drugs inhibit in vitro cholesterol efflux from human macrophage-derived foam cells
Laboratory Investigation, 09/25/09
Wang X et al. – Antioxidants including ginsenosides Rb1 and Rg1, S–allyl cysteine sulphoxide (SACS), simvastatin (SVT) and vitamin E significantly abolished HAART 3–plex–induced inhibition of cholesterol efflux. Therefore, HAART drugs significantly inhibit cholesterol efflux from human macrophage–derived foam cells through downregulation of caveolin–1 and increase of oxidative stress.
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