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See Latest ArticlesSuppression of ongoing experimental autoimmune myasthenia gravis by transfer of RelB-silenced bone marrow dentritic cells is associated with a change from a T helper Th17/Th1 to a Th2 and FoxP3+ regulatory T-cell profile
Inflammation Research, 09/24/09
Yang H et al. – RelB–silenced DCs were able to create a particular cytokine environment that was absent of inflammatory cytokines. RelB–silenced DCs provide a practical means to normalize the differentiation of the four T–cell subsets (Th17, Th1, Th2, and Treg) in vivo, and thus possess therapeutic potential in Th1/Th17–dominant autoimmune disorders such as myasthenia gravis.
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