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Can our understanding of epigenetics assist with primary prevention of congenital defects
Journal of Medical Genetics, 09/22/09

Martinez–Frias ML – This review summarizes the main epigenetic processes that influence gene expression and cell specification at different stages of development. The experimental and epidemiological evidence of environmental agents that cause epigenetic alterations is evaluated, as well as their effects in males and females. As a result, new avenues for primary prevention are proposed.

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GATA4 Mutations in Chinese Patients with Congenital Cardiac Septal Defects
Pediatric Cardiology, 11/19/09 Relevance Score: 68%

Late Pulmonary Valve Replacement in Congenital Heart Disease Patients Without Original Congenital Pulmonary Valve Pathology
Pediatric Cardiology, 11/19/09 Relevance Score: 67%

The Gerbode Defect: The Significance of a Left Ventricular to Right Atrial Shunt
Cardiology in the Young, 11/02/09 Relevance Score: 67%

Causes of death and cardiovascular complications in adolescents and adults with congenitally malformed hearts: an autopsy study of 102 cases
Cardiology in the Young, 10/19/09 Relevance Score: 67%

Variation in the Prevalence of Congenital Heart Defects by Maternal Race/Ethnicity and Infant Sex
The Journal of Pediatrics, 10/14/09 Relevance Score: 67%