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Phosphorothioate-Modified TLR9 Ligands Protect Cancer Cells against TRAIL-Induced Apoptosis
Journal of Immunology, 09/28/09
Chiron D et al. – The results suggest that the phosphorothioate modification of CpG ODNs could dampen the clinical efficacy of CpG ODN–based adjuvants by altering TRAIL/TRAIL receptor interaction.
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