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See Latest ArticlesMechanisms of Evasion of the Type I Interferon Antiviral Response by Flaviviruses
Journal of Interferon & Cytokine Research, 09/28/09
Diamond MS – Although the mechanistic details are still being dissected, new insight has emerged as to how a flavivirus minimizes the antiviral activity of type I interferon (IFN) to establish productive and potentially lethal infection. This review will summarize our current understanding of how mammalian cells recognize flaviviruses to induce an inhibitory IFN response and the countermeasures this group of viruses has evolved to antagonize this response.
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