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Opioid use affects antioxidant activity and purine metabolism: preliminary results
Human Psychopharmacology: Clinical and Experimental, 09/21/09
Mannelli P et al. – This is a preliminary investigation using metabolomics and showing multiple peripheral alterations of metabolic pathways in OD. Further studies should explore the metabolic profile of conditions of opioid abuse, withdrawal and long–term abstinence in relation to agonist and antagonist treatment and investigate biochemical signatures of opioid substances and medications.
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