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Cell-autonomous role of EphB2 and EphB3 receptors in the thymic epithelial cell organization
European Journal of Immunology, 09/29/09
Garcia–Ceca J et al. – The deficient lobes showed important alterations of the thymic epithelial organization as compared with the grafted WT lobes, but a less severe phenotype than the grafted EphB2–deficient thymus lobes, which confirms the relevance of EphB2 forward signal for the thymic epithelial organization but, also, a role of the reverse signaling in determining the final epithelial phenotype.
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