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See Latest ArticlesSmooth Muscle LDL Receptor–Related Protein-1 Inactivation Reduces Vascular Reactivity and Promotes Injury-Induced Neointima Formation
Arteriosclerosis, Thrombosis, and Vascular Biology, 09/09/09
Basford JE et al. – Smooth muscle expression of Lrp1 is important in maintaining normal vascular functions under normolipidemic conditions. The absence of Lrp1 expression results in greater smooth muscle cell proliferation, deficient contractile protein expression, impairment of vascular contractility, and promotion of denudation–induced neointimal hyperplasia.
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