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Tan SS et al. – The objective of this paper was to determine the cost effectiveness of exercise therapy (intervention group) compared with "usual care" (control group) in adolescents and young adults with the patellofemoral pain syndrome in primary care...The annual direct medical costs per patient were significantly higher for the intervention group (€434) compared with the control group mainly caused by additional physiotherapy visits. The average annual societal costs per patient were significantly lower in the intervention group. Productivity costs were the largest cost component, in particular costs due to reduced efficiency at paid work which were responsible for 47% and 56% of the total costs in the intervention and control group respectively. Patients in the intervention group experienced a slightly, but not significantly, higher quality of life (0.8722 vs 0.8617). With a cost effectiveness ratio of –€14 738 per quality adjusted life year, exercise therapy appears to be cost effective as compared with "usual care."

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