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See Latest ArticlesInterrelationships Among HDL Metabolism, Aging, and Atherosclerosis
Arteriosclerosis, Thrombosis, and Vascular Biology, 08/17/09
Walter M – A selection bias by HDL lowering genetic variation may explain why HDL deficiency is extremely rare among centenarians. Vice versa, HDL may modulate the aging process, not only by its well–known antiatherogenic effects, eg, its ability to remove cellular lipids and by antiatherogenic pleiotropic effects on cell survival, but possibly also by direct interfering with aging signaling or survival factor KLOTHO.
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