Your Messages Inbox
Most Viewed Abstracts
1. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease 2. Omega-3 fatty acids for bipolar disorder 3. Is folic acid good for everyone 4. ACS Releases Guidelines for HPV Vaccination 5. Vitamin D - A review Free full text
Your Article Summary
See Latest ArticlesTreatment of fibromyalgia syndrome with gabapentin and pregabalin – A meta-analysis of randomized controlled trials
Pain, 06/19/09
Häuser W et al. - Study concludes that the usage of gabapentin (GPT) and pregabalin (PGB) can be considered for the treatment of pain and sleep disturbances in FMS patients. Because of some dose-dependent relevant side effects of both drugs the treatment should start with low dosage and then increased slowly with small dosages.
Methods- Aim of this systematic review and meta-analysis was to determine the clinical relevance of GPT/PGB for the treatment of FMS
- MEDLINE, PsycINFO, SCOPUS, www.clinicaltrials.org, the Cochrane Library (through October 2008), and the reference sections of original studies on GPT/PGB in FMS were searched
- Randomized controlled trials (RCTs) on the treatment of FMS with GPT and PGB were analyzed
- 6/127 RCTs studying 2422 subjects on treatment with GPT (1 study) or PGB (5 studies) and 1056 subjects on placebo with a median treatment duration of 11wks were included
- Strong evidence for a reduction of pain, improved sleep and improved health-related quality of life (HRQOL) but not for depressed mood
- There was strong evidence for a non-substantial reduction of fatigue and of anxiety
- The external validity of the studies was limited because pts with severe somatic and mental disorders were excluded
Related Articles
Are chronic fatigue syndrome and fibromyalgia the same? Implications for the provision of appropriate mental health intervention
Journal of Psychiatric and Mental Health Nursing, 11/16/09
Relevance Score: 69%
The Predetermined Sites of Examination for Tender Points in Fibromyalgia Syndrome Are Frequently Associated With Myofascial Trigger Points
The Journal of Pain, 11/17/09
Relevance Score: 68%
Fibromyalgia and Myofascial Pain Syndrome - A Dilemma
Indian Journal of Anaesthesia, 10/22/09
Relevance Score: 68%
Sleep Apnea and Psychological Functioning in Chronic Fatigue Syndrome
Journal of Health Psychology, 11/04/09
Relevance Score: 67%
Patients' experiences of living with and receiving treatment for fibromyalgia syndrome: a qualitative study
BMC Musculoskeletal Disorders, 10/08/09
Relevance Score: 67%
Today in Clinical Pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
When Opioids Have Been Prescribed for Chronic Pain
Journal Of Pain & Palliative Care Pharmacotherapy, 12/02/09
Impaired Renal Function and Opioid Toxicity
Journal Of Pain & Palliative Care Pharmacotherapy, 12/02/09
Efficacy and safety of Creon 24,000 in subjects with exocrine pancreatic insufficiency due to cystic fibrosis
Journal of Cystic Fibrosis , 12/02/09
Today in Psychiatry...keeping you current
Receive free subspecialty "5-minute updates" via email
Screening for Depression in Adults: U.S. Preventive Services Task Force Recommendation Statement
Annals of Internal Medicine, 12/02/09
Increased Cold-Pain Thresholds in Major Depression
The Journal of Pain, 12/02/09
Mind the MIC: large variation among populations and methods
Journal of Clinical Epidemiology, 12/02/09
Sponsor
Article Search
Sponsor
Sponsor