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See Latest ArticlesHypertension in obstructive sleep apnea: Risk and therapy
Expert Review of Cardiovascular Therapy , 06/19/09
Das AM et al. – A review focuses on the pathophysiology and causal relationship between obstructive sleep apnea (OSA) and hypertension, as well as the cardiovascular effects of treatment of OSA.
Methods- Review of the risk of and therapy for hypertension in OSA
- OSA: risk factor for developing hypertension
- Pathophysiologic mechanism: distinctive pattern of intermittent hypoxia in OSA
- Pattern increases sympathetic tone, oxidative stress, inflammation and endothelial dysfunction
- These processes may lead to persistent elevation of blood pressure beyond obstructive events
- OSA: key part of workup for hypertensive pts
- Treatment of OSA with continuous positive airway pressure affects hypertension control and risk reduction of cardiovascular diseases
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