Your Article Summary
See Latest ArticlesAssociation between circulating osteoprogenitor cell numbers and bone mineral density in postmenopausal osteoporosis
Osteoporosis International, 06/12/09
Pirro M et al. – Study reports that in postmenopausal osteoporotic women, a reduced number of circulating AP+ cells and increased levels of AP+/CD34+, OCN+, and OCN+/CD34+ cells are associated with reduced bone mineral density (BMD).
Methods- Aim was to investigate if an association exists between the number of circulating osteoprogenitor cells and BMD in postmenopausal women with and w/o osteoporosis
- Number of circulating AP+, osteocalcin-positive (OCN+), AP+/CD34+, and OCN+/CD34+ cells was quantified in 54 postmenopausal osteoporotic women and 36 age-matched nonosteoporotic controls
- Number of AP+ cells was lower in osteoporotic women
- Higher levels of AP+/CD34+, OCN+, and OCN+/CD34+ cells were found in osteoporotic than controls
- Number of AP+ cells was correlated with lumbar BMD and proximal femur BMD
- Whereas inverse correlations were found between AP+/CD34+ cells, OCN+, OCN+/CD34+, and BMD
- Reduced AP+ cells and increased AP+/CD34?+, OCN+, and OCN+/CD34+ cells were predictors of low BMD, independent of traditional risk factors for osteoporosis
Today in Basic Science/Genetics...keeping you current
Receive free subspecialty "5-minute updates" via email
Advances in fibromyalgia treatment: understanding endogenous pain modulation
International Journal of Clinical Rheumatology, 11/09/09
Insights into the pathogenesis of axial spondyloarthropathy based on gene expression profiles
Arthritis Research & Therapy, 11/13/09
How triggers trigger acute migraine attacks: A hypothesis
Medical Hypotheses, 11/23/09
Today in Orthopedic/Physical Med...keeping you current
Receive free subspecialty "5-minute updates" via email
Osteonecrosis of the jaw correlated to bisphosphonate therapy in non-oncologic patients: Clinicopathological features of 24 patients
Journal of Rheumatology, 11/10/09
Effect of biomagnetic therapy versus physiotherapy for treatment of knee osteoarthritis: A randomized controlled trial
Journal of Rehabilitation Medicine, 11/20/09
Bisphosphonate therapy: When not to monitor BMD
The Journal of Family Practice, 11/02/09
Today in Women`s Health...keeping you current
Receive free subspecialty "5-minute updates" via email
FDA Approves Gardasil to Prevent Genital Warts in Males. Agency Also Approves Bivalent HPV Vaccine for Girls, Young Women
American Family Physician, 10/21/09
Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement
Annals of Internal Medicine, 11/17/09
Vitamin D insufficiency and health outcomes over 5 y in older women
American Journal of Clinical Nutrition, 11/13/09