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See Latest ArticlesContribution of Myeloperoxidase to Smoking-dependent Vascular Inflammation
Proceedings of the American Thoracic Society, 11/20/08
Rudolph TK et al. - Being stimulated by nicotine, neutrophils generate reactive oxygen species and release prooxidant enzymes like myeloperoxidase, which are capable of entering the vessel wall independently. Central mechanisms by which these enzymes can modulate the structural and functional integrity of the vessel wall have been characterized and increased the understanding of neutrophil-derived changes in vascular homeostasis in response to smoking and nicotine, respectively.
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