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Assessment of determinants for osteoporosis in elderly men
Osteoporosis International, 11/21/08
Scholtissen S et al. - Ageing, a lower BMI, higher type I collagen (CTX-1), family history, and prior fracture were associated with T-score. The algorithm presented in this study is a simple approach to identify men at risk for osteoporosis.
Methods- Study to identify some determinants associated to low bone mineral density in men and to develop a simple algorithm to predict osteoporosis
- 1,004 men, aged ≥60 yrs
- Biometrical, serological, clinical, and lifestyle determinants were collected
- Only age, BMI, CTX-1, and family history of osteoporosis and/or fracture were able to predict the femoral neck T-score
- When running the procedure with the total hip T-score, prior fracture also appeared to be significant
- With the lumbar spine T-score, only age, BMI, and CTX-1 were retained
- Best algorithm was based on age, BMI, family history, and CTX-1
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