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Morphometric vertebral fractures of the lower thoracic and lumbar spine, physical function and quality of life in men
Osteoporosis International, 10/02/08
Pasco JA et al. – Morphometric vertebral fracture (MVFs) are associated with poor quality of life and impaired physical function. It is recommended that morphometric X-ray absorptiometry be included in routine requests for bone densitometry because detection of MVFs has important implications for osteoporosis management in men.
Methods- Study to compare QoL and physical function in men with and w/o MVF
- MVFs were identified in a random sample of men aged 20–93 yrs
- Moderate and severe wedge, biconcave or compression deformities were classified as MVFs
- MVFs were identified in 64/1,147 men
- No MVFs were detected for men in their 20s
- Prevalence was 1.5% for 30–39 yrs, 1.4% 40–49 yrs, 3.2% 50–59 yrs, 4.7% 60–69 yrs, 10.0% 70–79 yrs and 14.6% 80+ yrs
- Among 555 men aged 60+ yrs, those with MVFs were twice as likely to have quality of life scores in the lowest tertile
- MVFs were associated with lower mean age-adjusted physical activity
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