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What Happened to Lithium? Antidepressant Augmentation in Clinical Settings
American Journal of Psychiatry, 07/04/06
Conclusion: Antidepressant augmentation is common in clinical settings. Although lithium currently has the most research support, antipsychotic medications and a second antidepressant are the most widely used augmenting agents. Many augmenting agents are used across clinical and demographic groups. Research is needed on the relative effectiveness of these agents, along with efforts to promote the use of agents with the greatest level of research support
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