Insulin-Stimulated Translocation of GLUT12 Parallels That of GLUT4 in Normal Muscle Stuart CA et al. - Insulin causes GLUT12 to translocate from an intracellular location to the plasma membrane in normal human skeletal muscle. Translocation of GLUT12 in cultured myoblasts was dependent of activation of PI3-K. GLUT12 may have evolutionarily preceded GLUT4 and now provides redundancy to the dominant GLUT4 system in muscle. [more...]
