High Preoperative Plasma Neopterin Predicts Delirium After Cardiac Surgery in Older Adults

Journal of the American Geriatrics Society, 03/23/2012

Preoperatively high neopterin levels predicted delirium after cardiac surgery in older adults, in addition to the well–known risk factors of poor cognitive function, high cardio–surgical risk, and combined coronary artery bypass graft (CABG) and valve surgery. Postoperative neopterin and HVA levels were also found to be associated with delirium, together with preoperative cognitive functioning. Plasma neopterin may be a candidate biomarker for delirium after cardiac surgery in these older adults.

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