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Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1-dependent pathways The Journal of Allergy and Clinical Immunology, 05/01/2012

Philbin VJ et al. – Imidazoquinolines (IMQs) Toll–like receptor (TLR)8 agonists engage adenosine–refractory TLR8 and inflammasome pathways to induce robust monocyte and monocyte–derived dendritic cells (MoDCs) activation and represent promising neonatal adjuvants.

Read this article on The Journal of Allergy and Clinical Immunology



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