Visceral adipose tissue predicts subclinical carotid atherosclerosis
As reported in Ultrasound in Medicine and Biology, ultrasound measurement of visceral adipose tissue, unlike the waist circumference, is associated with ultrasound-measured carotid intima-media thickness and an independent predictor of carotid plaques.
Tobacco and alcohol use significantly increase risk for ESCC
Based on a meta-analysis (n=5 studies) reported in the American Journal of Gastroenterology, the combined use of tobacco and alcohol increased the risk for esophageal squamous cell carcinoma (OR=3.28) compared with non-users; users of tobacco or alcohol alone had a 20%-30% increased risk of esophageal squamous cell carcinoma compared to non-users.
Combination tiotropium + formoterol superior to tiotropium alone in COPD patients
As reported in Pulmonary Pharmacology & Therapeutics, combination tiotropium (18 mcg) + formoterol (12 mcg) was superior to tiotropium alone in COPD (n=44) patients inadequately controlled with bronchodilator monotherapy. Combination therapy resulted in an increased bronchodilator response (FEV1 and FVC) and a maximum change in FEV1 and FVC over 24 h.