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Ranked, sorted, and summarized by MDLinx editors from the latest literature
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1 Benefit of early statin therapy in patients with acute myocardial infarction who have extremely low low-density lipoprotein cholesterol Full Text JACC - Journal of the American College of Cardiology, October 8, 2012 Original Publication Date: October 7, 2011    Clinical Article

2 Nurse prescribing in general practice: a qualitative study indicates increased job satisfaction and work-related stress Full Text Family Practice, October 8, 2012 Original Publication Date: October 7, 2011

3 Age-Specific Differences in Outcomes After Out-of-Hospital Cardiac Arrests Full Text Pediatrics, October 8, 2012 Original Publication Date: October 7, 2011

4 Relationship of Maternal Snuff Use and Cigarette Smoking With Neonatal Apnea Full Text Pediatrics, October 8, 2012 Original Publication Date: October 7, 2011

5 A prospective cohort study of health behavior profiles after age 50 and mortality risk Full Text BMC Public Health, October 8, 2012

6 Small proportions of actively-smoking patrons and high PM2.5 levels in southern California tribal casinos: support for smoking bans or designated smoking areas Full Text BMC Public Health, October 8, 2012

7 A Phase 1 dose-escalation study of the safety and pharmacokinetics of once-daily oral foretinib, a multi-kinase inhibitor, in patients with solid tumors Full Text Investigational New Drugs, October 8, 2012    Clinical Article

8 Incidence and Age-Specific Presentation of Restrictive Eating Disorders in Children: A Canadian Paediatric Surveillance Program Study Full Text Archives of Pediatrics and Adolescent Medicine, October 8, 2012 Original Publication Date: October 7, 2011

9 The short-term effect on alliance and satisfaction of using patient feedback scales in mental health out-patient treatment. A randomised controlled trial Full Text BMC Health Services Research, October 8, 2012

10 Phase I and pharmacokinetic study of pazopanib and lapatinib combination therapy in patients with advanced solid tumors Full Text Investigational New Drugs, October 8, 2012    Clinical Article

11 Pam50 breast cancer subtyping by RT-QPCR and concordance with standard clinical molecular markers Full Text BMC Genomics, October 8, 2012

12 Effect of vaccination with N-glycolyl GM3/VSSP vaccine by subcutaneous injection in patients with advanced cutaneous melanoma Full Text Cancer Management and Research, October 8, 2012

13 Patterns and socioeconomic influences of tobacco exposure in tobacco cultivating rural areas of Yunnan Province, China Full Text BMC Public Health, October 8, 2012

14 The I405V and Taq1B polymorphisms of the CETP gene differentially affect sub-clinical carotid atherosclerosis Full Text Lipids in Health and Disease, October 8, 2012

15 Predictors of overweight and obesity in adult women in Nairobi Province, Kenya Full Text BMC Public Health, October 8, 2012

16 Factors influencing participant enrolment in a diabetes prevention program in general practice: lessons from the Sydney diabetes prevention program Full Text BMC Public Health, October 8, 2012

17 Correlates of Delayed Sexual Intercourse and Condom Use among Adolescents in Uganda: a cross-sectional study Full Text BMC Public Health, October 8, 2012

18 Leisure time activities in adolescence in the presence of susceptibility genes for obesity: risk or resilience against overweight in adulthood? The HUNT study Full Text BMC Public Health, October 8, 2012

19 Analyses of body composition charts among younger and older Chinese children and adolescents aged 5 to 18 years Full Text BMC Public Health, October 8, 2012

20 Clinical, epidemiological, and spatial characteristics of Vibrio parahaemolyticus diarrhea and cholera in the urban slums of Kolkata, India Full Text BMC Public Health, October 8, 2012

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Highlights in Family Medicine

Belimumab safe and effective in childhood-onset SLE

As reported in Arthritis and Rheumatology, belimumab (a human monoclonal antibody targeting soluble B-lymphocyte stimulator) is effective and well-tolerated in children with SLE (n=7). The mean follow-up was 9.3 months. The SLEDAI decreased from 6.4 to 4 and 57% of recipients were able to taper steroids. Clinical response was evident by 3 months.

Tobacco and alcohol use significantly increase risk for ESCC

Based on a meta-analysis (n=5 studies) reported in the American Journal of Gastroenterology, the combined use of tobacco and alcohol increased the risk for esophageal squamous cell carcinoma (OR=3.28) compared with non-users; users of tobacco or alcohol alone had a 20%-30% increased risk of esophageal squamous cell carcinoma compared to non-users.

Triple therapy superior to dual therapy in HCV

As reported in Mayo Clinic Proceedings, treatment of hepatitis C virus-infected patients with triple therapy (pegylated-interferon, ribavirin, and teleprevir) is more effective than dual therapy (pegylated-interferon and ribavirin). Specifically, a sustained virologic response was achieved in 51% of treatment-naïve patients, 67% of patients with a prior non-response and 56% of patients with a prior relapse of patients treated with triple therapy compared to 37%, 11%, and 27% of patients treated with dual therapy, respectively.


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