Predictors of poor coronary collateral circulation in stable CAD
As reported in Angiology, the fasting blood glucose and serum uric acid levels and the white blood cell count were higher in patients with stable CAD (n=480) and associated with poor coronary collateral circulation.
Belimumab safe and effective in childhood-onset SLE
As reported in Arthritis and Rheumatology, belimumab (a human monoclonal antibody targeting soluble B-lymphocyte stimulator) is effective and well-tolerated in children with SLE (n=7). The mean follow-up was 9.3 months. The SLEDAI decreased from 6.4 to 4 and 57% of recipients were able to taper steroids. Clinical response was evident by 3 months.
Tobacco and alcohol use significantly increase risk for ESCC
Based on a meta-analysis (n=5 studies) reported in the American Journal of Gastroenterology, the combined use of tobacco and alcohol increased the risk for esophageal squamous cell carcinoma (OR=3.28) compared with non-users; users of tobacco or alcohol alone had a 20%-30% increased risk of esophageal squamous cell carcinoma compared to non-users.