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Family Medicine News & Articles

MDLinx Family Medicine stands out from other primary care literature review services because of our dedication to keeping our members current in less time. On a daily basis, receive an email with just the ‘headlines’ covering everything important that published in your specialty in the past 24 hours. Or, choose to Focus On the top articles published in the hottest topics in primary care, such as heart failure, depression, diabetes mellitus, eczema/psoriasis, infectious diseases, rheumatoid arthritis, COPD, and many more.

Additional bonus content is also available on this page, including clinical pearls from The Smartest Family Physician, a daily quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education. Additionally, enjoy the can’t-miss articles highlighted by our own physician editor, D. Scott Cunningham, MD, PhD.

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Articles

Latest (212) Full Text Articles (5432) Focus on Anxiety Disorders
Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Sofosbuvir for Previously Untreated Chronic Hepatitis C Infection Full Text New England Journal of Medicine, May 5, 2013    Clinical Article

2 Duration of protection against hepatitis A for the current two-dose vaccine compared to a three-dose vaccine schedule in children Vaccine , May 5, 2013    Clinical Article

3 Discordance Among Transient Elastography, Aspartate Aminotransferase to Platelet Ratio Index, and Histologic Assessments of Liver Fibrosis in Patients With Chronic Hepatitis C Clinical Gastroenterology and Hepatology , May 5, 2013    Clinical Article

4 Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus Alimentary Pharmacology and Therapeutics, May 5, 2013    Clinical Article

5 The safety and efficacy of peginterferon plus ribavirin in hepatitis C patients concomitant with malignancy other than hepatocellular carcinoma: a multicenter study Hepatology International, May 5, 2013    Clinical Article

6 Low hepatitis B envelope antigen seroconversion rate in chronic hepatitis B patients on long-term entecavir 0.5 mg daily in routine clinical practice European Journal of Gastroenterology & Hepatology, May 5, 2013    Clinical Article

7 Hepatitis B inactive carriers: Clinical course and outcomes Journal of Digestive Diseases, May 5, 2013    Clinical Article

8 Characterization of virologic escape in hepatitis C virus genotype 1b patients treated with the direct-acting antivirals daclatasvir and asunaprevir Journal of Hepatology, May 5, 2013    Clinical Article

9 Bezafibrate maintenance therapy in patients with advanced chronic hepatitis C European Journal of Gastroenterology & Hepatology, May 5, 2013    Clinical Article

10 Prevalence, Risk Factors, and Impact of Isolated Antibody to Hepatitis B Core Antigen and Occult Hepatitis B Virus Infection in HIV-1-Infected Pregnant Women Clinical Infectious Diseases, May 5, 2013    Clinical Article

11 Association between hepatitis B or hepatitis C virus infection and risk of pancreatic adenocarcinoma development: A systematic review and meta-analysis Pancreatology, May 5, 2013    Clinical Article

12 Sofosbuvir in combination with peginterferon alfa-2a and ribavirin for non-cirrhotic, treatment-naive patients with genotypes 1, 2, and 3 hepatitis C infection: a randomised, double-blind, phase 2 trial The Lancet Infectious Diseases, April 1, 2013    Clinical Article

13 Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial The Lancet, April 1, 2013    Clinical Article
Exclusive Author Commentary

14 Resolution of adefovir-related nephrotoxicity by adefovir dose-reduction in patients with chronic hepatitis B Alimentary Pharmacology and Therapeutics, April 1, 2013    Clinical Article

15 Hepatitis B virus infection status is an independent risk factor for multiple myeloma patients after autologous hematopoietic stem cell transplantation Tumor Biology, April 1, 2013    Clinical Article

16 Statins and the risk of hepatocellular carcinoma in patients with hepatitis C virus infection Journal of Clinical Oncology, April 1, 2013    Clinical Article

17 Cost-Effectiveness of Screening for Chronic Hepatitis C Infection in the United States Clinical Infectious Diseases, April 1, 2013

18 Eradication of Hepatitis C Virus Infection and the Development of Hepatocellular Carcinoma: A Meta-analysis of Observational Studies Full Text Annals of Internal Medicine, March 15, 2013    Continuing Medical Education    Review Article

19 Evaluation of the Hepatitis C Virus-Infected Patient: The Initial Encounter Clinical Infectious Diseases, March 15, 2013    Clinical Article

20 Prevention of mother-to-child transmission of hepatitis B virus (HBV) during pregnancy and the puerperium: Current standards of care Australian and New Zealand Journal of Obstetrics and Gynaecology, March 15, 2013    Clinical Article

21 Towards complete eradication of hepatitis B infection from perinatal transmission: review of the mechanisms of in utero infection and the use of antiviral treatment during pregnancy European Journal of Obstetrics & Gynecology and Reproductive Biology, March 15, 2013    Review Article

Clinical Pearls in Family Medicine

Highlights in Family Medicine

Vitamin D supplementation decreases systemic inflammation in T2DM

In a 12-week randomized, controlled trial, ingestion of a vitamin D-fortified yogurt (170 mg calcium + 500 IU vitamin D/250 mL; n=50) twice daily decreased markers of inflammation compared with placebo yogurt (170 mg calcium; n=50). Compared with baseline measures, the 25(OH)D levels were increased and the TNF-alpha, IL-6, hsCRP, SAA, and IL-10 levels were decreased in the group supplemented with vitamin D compared with the group that received placebo.

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Mediterranean diet associated with decreased diabetes, cardiovascular events, and all-cause mortality

Researchers at the University of Palermo conducted a study involving 9109 subjects with a mean follow-up of 6.2 years which showed that the subjects who adhered to a Mediterranean diet had increased dietary fiber, decreased total dietary fat, and an increased intake of monosaturated-to-saturated fats. Further, the incidence of diabetes, cardiovascular events, and all-cause mortality was lower in the subjects who followed a Mediterranean diet.

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Natalizumab superior to IFN-? 1a in MS patients

Based on a retrospective study conducted at the Federico II University (Naples), researchers have concluded that treatment of patients (n=84) with relapsing-remitting MS natalizumab for 12-24 months resulted in a greater reduction in disease activity (annualized relapse rate, .24 vs. .55, respectively) and disability progression than patients treated with INF-? 1a. The number of contrast-enhancing lesions was also less in the natalizumab-treated group.

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Most Popular Family Medicine Articles

Last month's top read Top Articles of 2012

1 A randomized trial of fish oil omega-3 fatty acids on arterial health, inflammation, and metabolic syndrome in a young healthy population Nutrition Journal, April 15, 2013    Free full text

2 Role of Garlic Usage in Cardiovascular Disease Prevention: An Evidence-Based Approach Evidence-based Complementary and Alternative Medicine , April 24, 2013    Free full text    Evidence Based Medicine

3 Beneficial effects of polyphenol-rich olive oil in patients with early atherosclerosis European Journal of Nutrition, April 1, 2013

4 Acute Consumption of Walnuts and Walnut Components Differentially Affect Postprandial Lipemia, Endothelial Function, Oxidative Stress, and Cholesterol Efflux in Humans with Mild Hypercholesterolemia The Journal of Nutrition, April 25, 2013

5 Walking Versus Running for Hypertension, Cholesterol, and Diabetes Mellitus Risk Reduction Arteriosclerosis, Thrombosis, and Vascular Biology, April 17, 2013

6 Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality- a review of recent evidence Autoimmunity Reviews, April 4, 2013
Exclusive Author Commentary

7 Associations of tea and coffee consumption with prostate cancer risk Cancer Causes and Control, April 22, 2013

8 The association between low vitamin D and depressive disorders Molecular Psychiatry, April 10, 2013    Free full text

9 Effects of vitamin D supplementation on body fat accumulation, inflammation, and metabolic risk factors in obese adults with low vitamin D levels -- Results from a randomized trial European Journal of Internal Medicine , April 11, 2013

10 Dietary advice for reducing cardiovascular risk Cochrane Reviews, April 1, 2013

11 Meat, fish, and esophageal cancer risk: a systematic review and dose-response meta-analysis Nutrition Reviews, April 15, 2013    Evidence Based Medicine    Review Article

12 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013    Evidence Based Medicine    Review Article

13 Omega-3 fatty acids and brain resistance to ageing and stress: Body of evidence and possible mechanisms Ageing Research Reviews, February 22, 2013    Review Article

14 Strong associations of 25-hydroxyvitamin D concentrations with all-cause, cardiovascular, cancer, and respiratory disease mortality in a large cohort study American Journal of Clinical Nutrition, March 4, 2013

15 The effect of vitamin D status on risk factors for cardiovascular disease Nature Reviews Nephrology, April 24, 2013    Review Article

16 Probiotics in colorectal cancer (CRC) with emphasis on mechanisms of actions and current prospectives Journal of Medical Microbiology, April 10, 2013

17 Oral nifedipine versus intravenous labetalol in hypertensive urgencies and emergencies of pregnancy: a randomized clinical trial Obstetric Medicine, April 2, 2013

18 Influence of Mediterranean diet on asthma in children: A systematic review and meta-analysis Pediatric Allergy and Immunology, April 15, 2013    Review Article

19 Can Vitamin D Supplementation Improve the Severity of Congestive Heart Failure? Congestive Heart Failure, April 2, 2013    Free full text

20 The Relationship of Sedentary Behavior and Physical Activity to Incident Cardiovascular Disease: Results from the Womens Health Initiative JACC - Journal of the American College of Cardiology, April 19, 2013

Indexed Journals in Family Medicine: American Family Physician, Archives of Family Med, Annals of Family Medmore

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