Family Medicine - Clinical Pharmacology News & Articles

MDLinx Family Medicine stands out from other primary care literature review services because of our dedication to keeping our members current in less time. On a daily basis, receive an email with just the ‘headlines’ covering everything important that published in your specialty in the past 24 hours. Or, choose to Focus On the top articles published in the hottest topics in primary care, such as heart failure, depression, diabetes mellitus, eczema/psoriasis, infectious diseases, rheumatoid arthritis, COPD, and many more.

Additional bonus content is also available on this page, including clinical pearls from The Smartest Family Physician, a daily quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education. Additionally, enjoy the can’t-miss articles highlighted by our own physician editor, D. Scott Cunningham, MD, PhD.

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Articles

Latest (15) Full Text Articles (829) Focus on HIV

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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161 Switch from selegiline to rasagiline is beneficial in patients with Parkinsons disease Journal of Neural Transmission, May 8, 2013 Clinical Article

162 Reactive Increase in Gastric Mucus Secretion Is an Adaptive Defense Mechanism Against Low-Dose Aspirin-Induced Gastropathy Digestive Diseases and Sciences, May 8, 2013 Clinical Article

163 Adherence Associated with Oral Medications in the Treatment of Spasticity PM&R, May 8, 2013 Clinical Article

164 B-Cell Depletion With Rituximab in Patients With Primary Biliary Cirrhosis Refractory to Ursodeoxycholic Acid The American Journal of Gastroenterology, May 8, 2013 Clinical Article

165 Lack of a Pharmacokinetic Interaction Between Treprostinil Diolamine and Sildenafil in Healthy Adult Volunteers Journal of Cardiovascular Pharmacology, May 8, 2013 Clinical Article

166 A randomised controlled trial of financial incentives to increase hepatitis B vaccination completion among people who inject drugs in Australia Preventive Medicine, May 8, 2013 Clinical Article

167 Clinical characteristics and effectiveness of lansoprazole in Japanese patients with gastroesophageal reflux disease and dyspepsia Journal of Gastroenterology, May 8, 2013 Clinical Article

168 Long-term follow-up of the FL2000 study comparing CHVP-interferon to CHVP-interferon plus rituximab in follicular lymphoma Full Text Haematologica, May 8, 2013 Clinical Article

169 Elevated PCSK9 Levels in Untreated Patients With Heterozygous or Homozygous Familial Hypercholesterolemia and the Response to High-Dose Statin Therapy Full Text Journal of the American Heart Association, May 8, 2013 Clinical Article

170 Deep brain stimulation of the subthalamic nucleus reverses oral tremor in pharmacological models of parkinsonism: interaction with the effects of adenosine A2A antagonism European Journal of Neuroscience, May 8, 2013 Review Article

171 Usefulness of omalizumab in ten patients with severe occupational asthma Allergy, May 7, 2013 Clinical Article

172 Real-life comparison of beclometasone dipropionate as an extrafine- or larger-particle formulation for asthma Respiratory Medicine, May 7, 2013 Clinical Article

173 Clinical effects of adalimumab treatment with concomitant azathioprine in Japanese Crohn’s disease patients Full Text World Journal of Gastroenterology, May 7, 2013 Clinical Article

174 Potential impact of new oral anticoagulants on the management of atrial fibrillation-related stroke in primary care International Journal of Clinical Practice, May 7, 2013 Clinical Article

175 Rituximab for the treatment of patients with autoimmune hepatitis who are refractory or intolerant to standard therapy, Canadian Journal of Gastroenterology, May 7, 2013 Clinical Article

176 Change in cholesterol absorption and synthesis markers in patients with coronary heart disease after combination therapy with simvastatin plus ezetimibe Full Text Chinese Medical Journal, May 7, 2013 Clinical Article

177 High Frequencies of Negative Pretreatment Results Following Presumptive Antibiotic Treatment for Chlamydia and Gonorrhea Southern Medical Journal, May 7, 2013 Review Article

178 Genome-wide association study of chemotherapeutic agents-induced severe neutropenia/leucopenia for patients in Biobank Japan Cancer Science, May 7, 2013 Clinical Article

179 Factors underlying regression of coronary atheroma with potent statin therapy European Heart Journal, May 6, 2013 Clinical Article

180 Phase I study of weekly kahalalide F as prolonged infusion in patients with advanced solid tumors Cancer Chemotherapy and Pharmacology, May 6, 2013 Clinical Article

50 available pages First Previous 9 10 11 12 13 14 15 16 17 18 Next Last

Clinical Pearls in Family Medicine

No relations were found between abdominal adipose tissue and bone mass, fat mass, blood pressure or triglyceride level in overweight adolescents
According to the Cleveland Clinic, the primary risk factors for coronary artery disease (CAD) are diabetes mellitus, family history, hypertension, hyperlipidemia, tobacco use and male gender
Untreated nocturnal gastroesophageal reflux has been demonstrated to be strongly associated with both respiratory and obstructive sleep apnea symptoms as well as airflow obstruction

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Family Medicine

Vitamin D supplementation decreases systemic inflammation in T2DM

In a 12-week randomized, controlled trial, ingestion of a vitamin D-fortified yogurt (170 mg calcium + 500 IU vitamin D/250 mL; n=50) twice daily decreased markers of inflammation compared with placebo yogurt (170 mg calcium; n=50). Compared with baseline measures, the 25(OH)D levels were increased and the TNF-alpha, IL-6, hsCRP, SAA, and IL-10 levels were decreased in the group supplemented with vitamin D compared with the group that received placebo.

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Mediterranean diet associated with decreased diabetes, cardiovascular events, and all-cause mortality

Researchers at the University of Palermo conducted a study involving 9109 subjects with a mean follow-up of 6.2 years which showed that the subjects who adhered to a Mediterranean diet had increased dietary fiber, decreased total dietary fat, and an increased intake of monosaturated-to-saturated fats. Further, the incidence of diabetes, cardiovascular events, and all-cause mortality was lower in the subjects who followed a Mediterranean diet.

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Natalizumab superior to IFN-? 1a in MS patients

Based on a retrospective study conducted at the Federico II University (Naples), researchers have concluded that treatment of patients (n=84) with relapsing-remitting MS natalizumab for 12-24 months resulted in a greater reduction in disease activity (annualized relapse rate, .24 vs. .55, respectively) and disability progression than patients treated with INF-? 1a. The number of contrast-enhancing lesions was also less in the natalizumab-treated group.

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Most Popular Family Medicine Articles

Last month's top read Top Articles of 2012

1 The Importance of 24-Hour Ambulatory Blood Pressure Monitoring in Patients at Risk of Cardiovascular Events High Blood Pressure & Cardiovascular Prevention, April 16, 2013

2 Oral nifedipine versus intravenous labetalol in hypertensive urgencies and emergencies of pregnancy: a randomized clinical trial Obstetric Medicine, April 2, 2013

3 Role of Ambulatory Blood Pressure Monitoring in Hypertension and Diabetes Current Hypertension Reports, April 19, 2013

4 Prolonged febrile seizures, clinical characteristics, and acute management Epilepsia, April 5, 2013

5 Osteoarthritis guidelines: a progressive role for topical nonsteroidal anti-inflammatory drugs Journal of Multidisciplinary Healthcare, April 4, 2013 Review Article Clinical Guideline

6 Meta-Analysis of Impact of Different Types and Doses of Statins on New-Onset Diabetes Mellitus The American Journal of Cardiology, April 4, 2013 Evidence Based Medicine Review Article

7 Cancer Immunotherapy: Present Status, Future Perspective, and a New Paradigm of Peptide Immunotherapeutics Discovery Medicine, April 1, 2013 Free full text Review Article

8 Corticosteroids for preventing postherpetic neuralgia Cochrane Reviews, April 2, 2013 Evidence Based Medicine

9 Vitamin D Levels for Preventing Acute Coronary Syndrome and Mortality: Evidence of a Non-Linear Association Journal of Clinical Endocrinology and Metabolism, March 27, 2013
Exclusive Author Commentary

10 Systematic review: pentoxifylline for the treatment of severe alcoholic hepatitis Alimentary Pharmacology and Therapeutics, April 3, 2013 Review Article

11 Association between maternal serum 25-hydroxyvitamin D level and pregnancy and neonatal outcomes: systematic review and meta-analysis of observational studies British Medical Journal, April 10, 2013 Free full text Review Article

12 HDL and Cholesterol: Life after the divorce? Journal of Lipid Research, March 26, 2013 Review Article

13 Branded Versus Generic Clopidogrel in Cardiovascular Diseases: A Systematic Review Journal of Cardiovascular Pharmacology, April 15, 2013 Evidence Based Medicine Review Article

14 Risk-Benefit Profile of Warfarin Versus Aspirin in Patients With Heart Failure and Sinus Rhythm: A Meta-analysis Circulation: Heart Failure, April 3, 2013 Evidence Based Medicine Review Article

15 A Possible New Option for Migraine Management: Agomelatine Clinical Neuropharmacology, April 3, 2013

16 Hypertension and antihypertensive drugs in pregnancy and perinatal outcomes American Journal of Obstetrics and Gynecology, April 15, 2013

17 In-treatment HDL cholesterol levels and development of new diabetes mellitus in hypertensive patients: The LIFE Study Diabetic Medicine, April 18, 2013

18 Antihypertensive treatment in diabetic patients- Review of current data Maturitas, April 15, 2013 Review Article

19 Update on the Antimicrobial Management of Foot Infections in Patients With Diabetes Clinical Diabetes, April 18, 2013 Free full text Review Article

20 Evidence for Therapeutic Uses of Nebulized Lidocaine in the Treatment of Intractable Cough and Asthma Annals of Pharmacotherapy, April 10, 2013 Review Article

Indexed Journals in Family Medicine: American Family Physician, Archives of Family Med, Annals of Family Med more

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Family Medicine - Clinical Pharmacology News & Articles

Articles

Clinical Pearls in Family Medicine

Highlights in Family Medicine

Vitamin D supplementation decreases systemic inflammation in T2DM

Mediterranean diet associated with decreased diabetes, cardiovascular events, and all-cause mortality

Natalizumab superior to IFN-? 1a in MS patients

Most Popular Family Medicine Articles

Other Topics in Family Medicine